background and objectives: the present work was carried out to investigate the ability of spirulina platensis to produce antimicrobial substance against bacteria and fungi.  materials and methods: the cells of the cyanobacterium were subjected to different extractions and the purified antagonistic compound proved to be effective against broad spectrum of bacteria and fungi. the antagonistic com...

Novel N-amino benzylthiolates were synthesized via multicomponent reaction of malononitrile, isothiocyanates and benzyl halides under conventional and solvent-free conditions. Various electron-donating and -withdrawing substitutes within both isothiocyanates and benzyl halides were used to demonstrate the efficiency of new methodology. A broad spectrum of antibacterial and antifungal activities...

endocarditis and intracardiac infection have been increased recently especially in dialysis dependent renal failure patients. this is usually intractable infection to broad spectrum antibiotic therapy and in most cases surgical intervention was necessary. we have presented 45 years old man with intracardiac infection at the tip of dialysis catheter that after catheter removal intracardiac infec...