نتایج جستجو برای: brine shrimp lethality test

تعداد نتایج: 834655  

Journal: :Brazilian journal of biology = Revista brasleira de biologia 2012
D D R Arcanjo A C M Albuquerque B Melo-Neto L C L R Santana M G F Medeiros Amgl Citó

The brine shrimp (Artemia salina Leach) lethality bioassay offers an advantage in standardization and quality control of botanical products. This test is well correlated with antitumor activity (cytotoxicity) and can be used to monitor the activity of bioactive natural products. This paper reports the bioactivity of ethanol extracts from seven medicinal plants from the Northeast of Brazil (Acme...

Journal: :Anais da Academia Brasileira de Ciencias 2008
Celso A Camara Tania M S Silva Thiago G da-Silva Rodrigo M Martins Ticiano P Barbosa Angelo C Pinto Maria D Vargas

The toxic profile of lawsone (2-hydroxy-[1,4]naphthoquinone) and a series of [1,4]naphthoquinone derivatives was evaluated against the brine shrimp Artemia salina and against the mollusk Biomphalaria glabrata, the main transmitting vector of schistosomiasis in Brazil. Of the seventeen compounds tested nine fell below the threshold of 100 microg/mL set for potential molluscicidal activity by the...

2013
BADRUN NAHER CHOWDHURY MOZAMMEL HAQUE HOSSAIN SOHRAB FARHANA AFROZ M. A. AL-MANSUR TAMANNA SULTANA CHOUDHURY MAHMOOD HASAN

Three steroids, namely 24-ethyl-5α-cholestan-3-one (1), 5α-stigmast-22-en-3-one (2), stigmast-5, 22-dien-3-one (3) have been isolated from N. stellata. The phytochemical and antimicrobial as well as cytotoxic activities of Nymphaea stellata were investigated in this study. Crude extracts of N. stellata and various column fractions exhibited poor antimicrobial activity against a wide range of Gr...

2009
Farzana Alam Mohammad S. Rahman Md. Shahanur Alam Md. Khalid Hossain Md. Aslam Hossain Mohammad A. Rashid

Lupeol (1), epilupeol (2) and β-sitosterol (3) were isolated from the n-hexane and the carbon tetrachloride soluble fraction of a methanol extract of the leaves of Phoenix paludosa Roxb. The n-hexane, carbon tetrachloride and chloroform soluble materials from the concentrated methanol extract were subjected to antimicrobial screening and brine shrimp lethality bioassay. All of the partitionates...

2016
Abdolrasoul Haghir Ebrahimabadi Mohammad Mahdi Movahedpour Hossain Batooli Ebrahim Haghir Ebrahimabadi Asma Mazoochi Maryam Mobarak Qamsari

OBJECTIVES Mindium laevigatum is an endemic plant of Iran and Turkey and is widely used as blood purifier, antiasthma and antidyspnea in traditional medicine. Chemical composition of volatile materials of the plant and its antioxidant, antimicrobial and cytotoxic activities were reported in this study. MATERIALS AND METHODS Simultaneous distillation-extraction (SDE) and GC-Mass-FID analysis w...

Journal: :Chemical & pharmaceutical bulletin 2002
Jian-Mei Huang Kousuke Nakade Mamiko Kondo Chun-Shu Yang Yoshiyasu Fukuyama

In the study of bioactive substances in Illicium plants, the methanol extract of I. merrillianum showed brine shrimp lethality test (BST) activity at 200 microg/ml. Bioassay-guided fractionation of the BST active fractions resulted in the isolation of 4-O-methyleudesm-11-en-4alpha-ol, eudesmol-11-en-4alpha-ol and (-)-hinokinin as potent BST active compounds. On the other hand, four new highly o...

2012
Yi Liang Xiao-Ming Li Chuan-Ming Cui Chun-Shun Li Hong Sun Bin-Gui Wang

In addition to 13 known compounds, four new bisabolane sesquiterpenes, okamurenes A-D (1-4), a new chamigrane derivative, okamurene E (5), and a new C₁₂-acetogenin, okamuragenin (6), were isolated from the marine red alga Laurencia okamurai. The structures of these compounds were determined through detailed spectroscopic analyses. Of these, okamurenes A and B (1 and 2) are the first examples of...

Journal: :Pakistan journal of pharmaceutical sciences 2013
Sarwat Jahan Shamim Akhtar Zafar Saied Saify Nousheen Mushtaq Ali Akbar Sial Arfa Kamil Muhammed Arif

Synthesis of novel phenacyl derivatives of alkyl piperidine as cytotoxic agents via simple and single step reaction procedure is going to be reported here. Twelve new compounds were successfully synthesized in moderate yield and in solid form. Their synthesis was confirmed by TLC, melting point, CHN analysis and through different spectral studies such as UV, IR, Mass and proton NMR. The advanta...

2014
Chun-Yan An Xiao-Ming Li Chun-Shun Li Gang-Ming Xu Bin-Gui Wang

Three new indolediketopiperazine peroxides, namely, 24-hydroxyverruculogen (1), 26-hydroxyverruculogen (2), and 13-O-prenyl-26-hydroxyverruculogen (3), along with four known homologues (4-7), were isolated and identified from the culture extract of the marine sediment-derived fungus Penicillium brefeldianum SD-273. Their structures were determined based on the extensive spectroscopic analysis a...

Journal: :Revista Argentina de microbiologia 2016
André de O Feitosa Amanda Cristina S Dias Gisele da C Ramos Heriberto R Bitencourt José Edson S Siqueira Patrícia Santana B Marinho Andersson Barison Fernanda M M Ocampos Andrey Moacir do R Marinho

Endophytic fungi are fungi that colonize internal tissues of plants; several biologically active compounds have been isolated from these fungi. There are few studies of compounds isolated from endophytic fungi of Amazon plants. Thus, this study aimed the isolation and structural identification of ergosterol (1), ergosterol peroxide (2), mevalonolactone (3), cytochalasin B (4) and cytochalasin H...

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