mammography has been recognized as the best method of screening for breast cancer, for a long time. although the sensitivity of mammography is acceptable, it has limited specificity and a radiologist should be aware of limitations and pitfalls. there are different positive findings in mammography which are descriptors of breast disease including benign lesions or breast cancer. in this talk i w...

Background and Objective: Anti-CK5/6 monoclonal antibodies have an established role in breast disease diagnosis. Anti-CK5 monoclonal antibodies have recently become commercially available. There has been growing interest in the staining characteristics of anti-CK5 and its potential diagnostic role in place of anti-CK5/6. We aim to compare and contrast the staining characteristi...

Cutaneous Crohn’s disease (CCD) is a relatively rare disease. Two-thirds of the affected patients are female with a mean age of onset of 35 years. CCD is divided into a genital type and an extra-genital type, each with their own unique different clinical manifestations. The usual presentation of genital Crohn’s disease (CD) is in the form of erythema and edema of the labia and scrotum. Here, we...

Background & objective: Globally, breast cancer is the most common malignancy among females. Prohibition (PHB)-I, a homologous protein, was initially introduced as a suppressor gene for amplification process. Further, the protein has a key role in the cell cycle and is capable of inhibiting DNA transcription in many cell types. Therefore, its possible role in different...

Backgrounds: Chemotherapy for treatment of breast cancer uses some drugs to target and destroy the cancer cells. However, most of antineoplastic treatments are non-specific and the innate cells will be damaged. In this study, the effect of Adriamycin/Cytoxan (AC) chemotherapy on status of antioxidant enzymes and Se levels in breast cancer patients was evaluated. Methods: A prospective study, i...

OBJECTIVE To assess the public health significance of premature weaning of infants from breast milk on later-life risk of chronic illness. DESIGN A review and summary of recent meta-analyses of studies linking premature weaning from breast milk with later-life chronic disease risk is presented followed by an estimation of the approximate exposure in a developed Western country, based on histo...

BACKGROUND Periodontal disease has been consistently associated with chronic disease; there are no large studies of breast cancer, although oral-associated microbes are present in breast tumors. METHODS In the Women's Health Initiative Observational Study, a prospective cohort of postmenopausal women, 73,737 women without previous breast cancer were followed. Incident, primary, invasive breas...

Cancer is a disease caused by uncontrollable cell growth. The constant subject of concern due to unavailability treatment at severe level. Patients who have suffered from the chance getting saved if this fatal illness identified in beginning stage. survival will be very low it detected final stage cancer. As patients could not survive their last stage, cure disease, an early diagnosis key issue...

breast cancer is the most common malignancy in women in many parts of the world. the risk factors for breast cancer cover a broad range of conditions, from age to complex genetic alterations. present data is showing an increase in the annual incidence rates of disease and it is ranked as the first recorded malignancies among iranian women after 1999. to study the association of reproductive and...

Locally advanced disease Patients with locally advanced breast cancer do not have distant metastatic disease and are in this group based on tumor size and/or nodal status. Such patients often present with a large breast mass or axillary nodal disease, which is easily palpable on physical examination. In some instances, the breast is diffusely infiltrated with disease, and no dominant mass is ev...