Since breast-conserving surgery has become the gold standard for early breast cancer, the development of less radical or less burdensome technologies has been pressed for in order to preserve the patient from unnecessary harm through the operative procedure. Different technical approaches are under evaluation, and some of them are already being used in the clinical setting. The aim of this arti...

background: we studied the patterns of premenopausal and postmenopausal breast cancer incidence and its established risk factors in iran in 2010. in addition, we estimated the 5-year prevalence of breast cancer in the country. methods: we performed an internet and library literature review. we used national cancer registry data, demographic health surveys, national censuses and world bank data ...

breast cancer is the most common cancer occurring among women. the mortality rate of breast cancer can be reduced by regular breast cancer screening program. this study was carried out to identify the knowledge and practice of women about breast cancer screening in zahedan, southeast of iran. in this cross- sectional study, 384 women were selected as an improbability sample of women referring t...

background: breast cancer is the most common malignancy in women. breast cancer type 1 susceptibility gene (brca1) is a tumor suppressor gene, involved in dna damage repair and in 81% of the breast-ovarian cancer families were due to brca1. in some clinically investigated genes, the intragenic marker polymorphism is important and the screening of such mutations is faster by using short tandem r...

Neelam Sood, Nisha Sehrawat* Department of Pathology, Deen Dayal Upadhya Hospital, New Delhi, India The term gestational breast cancer is defined as breast cancer diagnosed during pregnancy and up to 1 year postpartum. Overall incidence rate is 0.7 – 3.8% . These lesions are generally missed on radiology as well as cytology due to physiological and functional changes in mammary gland or misdiag...

Adipose-derived stem cells (ADSCs) are rapidly becoming the gold standard cell source for tissue engineering strategies and hold great potential for novel breast reconstruction strategies. However, their use in patients with breast cancer is controversial and their oncological safety, particularly in relation to local disease recurrence, has been questioned. In vitro, in vivo, and clinical stud...

UNLABELLED We recently developed a small molecule inhibitor SMI#9 for Rad6, a protein overexpressed in aggressive breast cancers and involved in DNA damage tolerance. SMI#9 induces cytotoxicity in cancerous cells but spares normal breast cells; however, its therapeutic efficacy is limited by poor solubility. Here we chemically modified SMI#9 to enable its conjugation and hydrolysis from gold na...

background: breast cancer incidence has increased rapidly inkuwait, but there haven’t been any studies investigating the recognized risk factors of breast cancer inkuwait. the aim of the study was to investigate breast cancer risk factors among women inkuwait.   methods: a case-control study was conducted in kuwait from may 2003 to march 2004 using a questionnaire including socio-demographic da...

background: modified radical mastectomy (mrm) is still one of globally accepted surgical techniques for breast cancer and in some selected patient is the gold standard type of surgery. the most frequent complication of this procedure is seroma under skin flaps or in the axilla as reported as much as 30% in some studies. the use of closed suction drainage system to reduce the incidence of this c...

F18 2-Fluoro 2-deoxyglucose (FDG) has been the gold standard in positron emission tomography (PET) oncologic imaging since its introduction into the clinics several years ago. Seeking to complement FDG in the diagnosis of breast cancer using radio labeled fructose based analogs, we investigated the expression of the chief fructose transporter-GLUT 5 in breast cancer cells and human tissues. Our...