We have previously reported the identification and characterization of a prolactin-inducible protein (PIP) as well as the cloning of the gene encoding PIP in cultured human breast cancer cells. We now present three lines of evidence that the gene encoding PIP is also expressed by some human breast cancers in vivo: (a) detection of PIP immunoreactivity in the serum of some breast cancer patients...

background dynamic contrast-enhanced magnetic resonance imaging (dce - mri) has been widely used in the management of breast cancer, and its diagnostic value in breast imaging has been demonstrated. there have only been a few reports regarding the usefulness of pre-contrast imaging. knowledge about clinically significant findings of preoperative, pre-contrast t1 and t2 mr images will allow more...

Background: Touch imprint cytology is an easy and rapid method of evaluation of cancers. It can be utilized as a rapid intraoperative method and on site evaluation of biopsy specimen. Aim: to evaluate the efficacy of touch imprint cytology in assessment of adequacy of needle core biopsy of breast lumps its diagnostic accuracy for malignancy. Material and methods: A total of 160 cases of core ne...

In this paper, we evaluate the radiological features of pregnancy-associated breast lesions and discuss the difficulties in diagnosis by imaging. We selected patients who were diagnosed with pregnancy-associated breast lesions during the previous 5 years. All patients complained of palpable lesions in the breast and underwent ultrasonographic (US) examination, the first choice for examination o...

BACKGROUND Current guidelines recommend minimally invasive breast biopsy (MIBB) as the gold standard for the diagnosis of breast lesions. The purpose of this study was to describe geographic patterns and time trends in the use of MIBB in Texas. METHODS We used 100% Texas Medicare claims data (2000-2008) to identify women older than 66 years of age who underwent breast biopsy. Biopsies were cl...

BACKGROUND The aim of this study was to assess the diagnostic performance of stereotactic core needle breast biopsy using spring-loaded or vacuum-assisted techniques for impalpable microcalcification lesions in Taiwanese women. METHODS We retrospectively reviewed the data of patients who received stereotactic core needle breast biopsy for impalpable mammographic microcalcification lesions fro...

OBJECTIVE The purpose of this study to present the results of Magnetic resonance imaging (MRI) guided cutting needle biopsy procedures of suspicious breast lesions that can be solely detected on Magnetic resonance (MR) examination. MATERIALS AND METHODS The study included 48 patients with 48 lesions which were solely be observed in breast MRI, indistinguishable in ultrasonography and mammogra...

juvenile fibroadenoma is an uncommon histologic variant of fibroadenoma that frequently shows a remarkable and rapid growth. the development of a carcinoma within a fibroadenoma, either in situ or invasive, is a rare condition. we encountered a 36-year-old woman with a palpable mass in the right breast. the radiologic findings were indicative of a fibroadenoma in the breast. sonographic guided ...

Ectopic breast tissue has the ability to undergo all the pathological changes of the normal breast, including breast cancer. Gastrointestinal metastasis of breast cancer is rarely observed and it is very difficult to differentiate gastric metastases from primary gastric cancer. We present a case of 52-year-old female, who suffered from abdominal pain. Physical examination showed a palpable mass...

We propose the use of a robust, biopsy needle-based, fiber-optic tool for routine clinical quantification of tumor oxygenation at the time of diagnostic biopsy for breast cancer. The purpose of this study was to show diffuse reflectance spectroscopy as a quantitative tool to measure oxygenation levels in the vascular compartment of breast cancers in vivo via an optical biopsy technique. Thirty-...