Apart from pituitary adenomas, a number of tumours may arise from within the sella presenting a diagnostic and therapeutic challenge at a multidisciplinary specialist level. This article focus on the most commonly diagnosed non-adenomatous pituitary tumours (craniopharyngiomas, Rathke's cleft cysts and meningiomas) and provides data on their pathogenesis, diagnosis and treatment.

This case report describes the airway management of three month old child presenting with a severe facial congenital malformation, a bilateral Tessier number 4 cleft, and scheduled to undergo benign eye surgery. The use of a conventional laryngeal mask allowed successful management, despite the severity of the facial abnormality. This case is then discussed at the light of the literature.

Cysts commonly occurring in the neck include thyroglossal cyst and dermoid cysts in the midline, cystic thyroid nodules, branchial cysts and cystic Hygroma in the lateral neck. Hydatid cyst disease is commonly seen in the right lobe of the liver, the lung and rarely in other parts of the body. In general, cysts in the neck are not common in the second decade of life. In this article, we present...

Sarday, M ay 6, 2017 RESULTS: In vitro analysis of mesenchymal cells carrying the Ad.Flp/Ad.Cre construct demonstrated a significant loss in osteogenic potential (p<0.05) and pSMAD1/5 signaling in the absence of Tak1. Reactivation of Tak1 was sufficient to restore pSMAD1/5 signaling and osteogenic differentiation. Tak1 knockout demonstrated an opposite effect on cell proliferation with immediat...

Three Na(+)-K(+)-ATPase (nka) α-subunit isoforms, nka α1a, nka α1b, and nka α1c, were identified from gills of the freshwater climbing perch Anabas testudineus. The cDNA sequences of nka α1a and nka α1b consisted of 3,069 bp, coding for 1,023 amino acids, whereas nka α1c was shorter by 22 nucleotides at the 5' end. In freshwater, the quantity of nka α1c mRNA transcripts present in the gills was...

Heterotopic salivary-gland tissue Fistula in the lower neck Congenital abnormality Abstract Heterotopic islands of salivary-gland tissue are rare and have been described in a number of sites in the head and neck. We describe a patient with salivary-gland fistulas in the lower third of the neck, without evidence of any other congenital abnormalities. The appearance of sinuses in association with...

We report and discuss the rare case of a pituitary abscess forming within a Rathke's cleft cyst (RCC). A 66-year-old gentleman presented with visual deterioration and symptoms suggestive of hypopituitarism. The patient underwent transsphenoidal debulking of the lesion whereupon purulent material was discovered. Histological examination was suggestive of RCC together with numerous neutrophils ch...

The spatio-temporal expression of connexin43 in Xenopus laevis embryos was studied by in situ hybridization. Cx43 expression is first detected at stage 25 in the developing eye. In stage 32, expression was found in the margin of the lens placode, the cement gland, notochord, and in stage 37 in the branchial arches. Early limb buds show strong expression of Cx43 distally while later on expressio...

Volume 5 • Issue 6 • 1000173 J Health Med Inform ISSN: 2157-7420 JHMI, an open access journal Latest studies concerning the psychological impact of orofacial cleft showed that, with the improvements in surgery and with adequate multidisciplinary support, clefts were no more associated with major psychological problems. However, the growth of humanitarian craniofacial care, as well as the increa...

UNLABELLED Cleft lip and palate (CL/P) are the most common congenital craniofacial anomalies. AIM To evaluate environmental risk factors for non-syndromic CL/P in a reference care center in Minas Gerais. MATERIALS AND METHODS we carried out a case-controlled study, assessing 100 children with clefts and 100 children without clinical alterations. The analysis dimensions (age, skin color, gen...