Slow waves are the most prominent electroencephalographic (EEG) feature of sleep. These waves arise from the synchronization of slow oscillations in the membrane potentials of millions of neurons. Scalp-level studies have indicated that slow waves are not instantaneous events, but rather they travel across the brain. Previous studies of EEG slow waves were limited by the poor spatial resolution...

Various electrocardiographic changes have been reported in the setting of acute neurological events, among them large, upright U waves. In contrast, the occurrence of inverted U waves is strongly suggestive of cardiovascular disease, most commonly hypertension, coronary artery disease, or valvular abnormalities. Presented herein is the case of a 29-year-old man with previous anoxic brain injury...

This paper presented the technique of robot control by event-related potentials (ERPs) of brain waves. Based on the proposed technique, severe physical disabilities can free browse outside world. A specific component of ERPs, N2P3, was found and used to control the movement of robot and the view of camera on the designed brain-computer interface (BCI). Users only required watching the stimuli o...

Two models of the neocortex are developed to study normal and pathological neuronal activity. One model contains a detailed description of a neocortical microcolumn represented by 656 neurons, including superficial and deep pyramidal cells, four types of inhibitory neurons and realistic synaptic contacts. Simulations show that neurons of a given type exhibit similar behavior in this detailed mo...

Impulsivity has proven to be an important psychological construct reflected in both normal and pathological human behaviors and traits. However, the definition, measurement, and manifestations of the construct are varied and multifarious. Impulsive behaviors are observed in a wide range of psychiatric/behavioral disorders, including alcohol/substance use and abuse disorders (AUDs/SUDs), conduct...

The mechanisms by which blast pressure waves cause mild-to-moderate traumatic brain injury (mTBI) are an open question. Possibilities include acceleration of the head, direct passage of the blast wave via the cranium, and propagation of the blast wave to the brain via a thoracic mechanism. The hypothesis that the blast pressure wave reaches the brain via a thoracic mechanism is considered in li...

Objective: Determine the role of magnetoencephalography (MEG) in evaluating sports-related concussions. Subject: A professional indoor soccer player who suffered his fifth concussion. Methods: The subject underwent neuropsychological testing to assess a variety of brain functions. Brain MRI and MEG were subsequently performed at the University of California, San Diego Radiology Imaging Lab-MEG ...