نتایج جستجو برای: brain volumes

تعداد نتایج: 519830  

2013
David Alexander Dickie Dominic E. Job David Rodriguez Gonzalez Susan D. Shenkin Trevor S. Ahearn Alison D. Murray Joanna M. Wardlaw

BACKGROUND Statistical models of normal ageing brain tissue volumes may support earlier diagnosis of increasingly common, yet still fatal, neurodegenerative diseases. For example, the statistically defined distribution of normal ageing brain tissue volumes may be used as a reference to assess patient volumes. To date, such models were often derived from mean values which were assumed to represe...

Journal: :Human brain mapping 2017
Rachel M Brouwer Matthew S Panizzon David C Glahn Derrek P Hibar Xue Hua Neda Jahanshad Lucija Abramovic Greig I de Zubicaray Carol E Franz Narelle K Hansell Ian B Hickie Marinka M G Koenis Nicholas G Martin Karen A Mather Katie L McMahon Hugo G Schnack Lachlan T Strike Suzanne C Swagerman Anbupalam Thalamuthu Wei Wen John H Gilmore Nitin Gogtay René S Kahn Perminder S Sachdev Margaret J Wright Dorret I Boomsma William S Kremen Paul M Thompson Hilleke E Hulshoff Pol

Structural brain changes that occur during development and ageing are related to mental health and general cognitive functioning. Individuals differ in the extent to which their brain volumes change over time, but whether these differences can be attributed to differences in their genotypes has not been widely studied. Here we estimate heritability (h2 ) of changes in global and subcortical bra...

Journal: :The American journal of psychiatry 2008
Yvette I Sheline Joseph L Price S Neil Vaishnavi Mark A Mintun Deanna M Barch Adrian A Epstein Consuelo H Wilkins Abraham Z Snyder Lars Couture Kenneth Schechtman Robert C McKinstry

OBJECTIVE Segmented brain white matter hyperintensities were compared between subjects with late-life depression and age-matched subjects with similar vascular risk factor scores. Correlations between neuropsychological performance and whole brain-segmented white matter hyperintensities and white and gray matter volumes were also examined. METHOD Eighty-three subjects with late-life depressio...

Journal: :Neurobiology of aging 2015
Christina P Boyle Cyrus A Raji Kirk I Erickson Oscar L Lopez James T Becker H Michael Gach W T Longstreth Leonid Teverovskiy Lewis H Kuller Owen T Carmichael Paul M Thompson

The purpose of this study was to use a novel imaging biomarker to assess associations between physical activity (PA), body mass index (BMI), and brain structure in normal aging, mild cognitive impairment, and Alzheimer's dementia. We studied 963 participants (mean age: 74.1 ± 4.4 years) from the multisite Cardiovascular Health Study including healthy controls (n = 724), Alzheimer's dementia pat...

Journal: :Magnetic resonance imaging 2013
Ravi Bansal Xuejun Hao Feng Liu Dongrong Xu Jun Liu Bradley S Peterson

Water content is the dominant chemical compound in the brain and it is the primary determinant of tissue contrast in magnetic resonance (MR) images. Water content varies greatly between individuals, and it changes dramatically over time from birth through senescence of the human life span. We hypothesize that the effects that individual- and age-related variations in water content have on contr...

Journal: :AJNR. American journal of neuroradiology 2010
A Horská A Laclair M Mohamed C T Wells T McNutt K J Cohen M Wharam E M Mahone W Kates

BACKGROUND AND PURPOSE Injury of the cerebellar vermis may occur in children with brain malignancies. Because the vermis is involved in motor and cognitive functioning, the goal of this prospective longitudinal study was to evaluate treatment-related changes in vermal volumes and neuropsychologic performance in children receiving brain radiation of the cerebellum. MATERIALS AND METHODS Ten pa...

Journal: :Journal of the Neurological Sciences 2021

The relationship between optical coherence tomography (OCT) measurements of the retinal structures has been described for various neurological diseases including Multiple Sclerosis (MS), Alzheimer's disease (AD) and Parkinson's (PD). Brain volume changes, both globally by area, are associated with some these same diseases, yet correlation OCT is not fully elucidated.Our study looked at normal s...

Journal: :Brain : a journal of neurology 2015
Vladimir V Senatorov Ruslan Damadzic Claire L Mann Melanie L Schwandt David T George Daniel W Hommer Markus Heilig Reza Momenan

The insula, a structure involved in higher order representation of interoceptive states, has recently been implicated in drug craving and social stress. Here, we performed brain magnetic resonance imaging to measure volumes of the insula and amygdala, a structure with reciprocal insular connections, in 26 alcohol-dependent patients and 24 healthy volunteers (aged 22-56 years, nine females in ea...

Journal: :Magnetic resonance imaging 2011
Ramon Casanova Mark A Espeland Joseph S Goveas Christos Davatzikos Sarah A Gaussoin Joseph A Maldjian Robert L Brunner Lewis H Kuller Karen C Johnson W Jerry Mysiw Benjamin Wagner Susan M Resnick

Use of conjugated equine estrogens (CEE) has been linked to smaller regional brain volumes in women aged ≥65 years; however, it is unknown whether this results in a broad-based characteristic pattern of effects. Structural magnetic resonance imaging was used to assess regional volumes of normal tissue and ischemic lesions among 513 women who had been enrolled in a randomized clinical trial of C...

2017
Austin T. Mudd Joanne E. Fil Laura C. Knight Ryan N. Dilger

Background Iron deficiency is the most common micronutrient deficiency worldwide and children are at an increased risk due to the rapid growth occurring during early life. The developing brain is highly dynamic, requires iron for proper function, and is thus vulnerable to inadequate iron supplies. Iron deficiency early in life results in altered myelination, neurotransmitter synthesis, neuron m...

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