conclusions we described a rare case of a usually aggressive thyroid angiosarcoma in a patient living in a non-alpine region, with an unusual favorable outcome after the operation and radiotherapy. case presentation an asymptomatic 61-year-old woman presented with a right lobe thyroid nodule with fine needle aspiration cytology indicating “suspicious for malignancy” was reported in our study. h...

A true collision tumor is a rare entity composed of two histologically distinct neoplasms coinciding in the same organ. This paper reports a unique case of cerebral collision tumor consisting of two benign components. On the first hand, meningioma which is usually a benign lesion arising from the meningothelial cell in the arachnoidal membrane. On the other, cerebral cavernoma which is a well-c...

Introduction: The brain tumor is an abnormal growth of tissue in the brain, which is one of the most important challenges in neurology. Brain tumors have different types. Some brain tumors are benign and some brain tumors are cancerous and malignant. Glioblastoma Multiforme (GBM) is the most common and deadliest malignant brain tumor in adults. The average survival rate for peo...

Abstract Glioblastoma (GB) is the most common and aggressive adult brain tumor with no cure. Brain stem cells (BTSCs) are a rare population of self-renewing multipotent in GB that contribute to tumorigenesis, therapeutic resistance, tumour recurrence. Here, we report CDK2 inhibitor suppresses BTSCs via OSM/OSMR/STAT3 signalling pathway. To begin with, performed high throughput screening (HTS) ~...

Detecting a new area of contrast-enhancement at MRI after irradiation of malignant brain tumor arises the problem of differential diagnosis between tumor recurrence and radiation necrosis induced by the treatment. The challenge for imaging is to distinguish the two diagnoses given: the prognostic and therapeutic issues. Various criteria have been proposed in the literature based on morphologica...

We report our experiences of four cases with meningeal hemangiopericytoma treated with surgery and postoperative radiotherapy and survey the literature to elucidate the efficacy of radiotherapy. Patients were treated with surgical resection and 46-52 Gy postoperative radiotherapy. Three patients had local control for 30, 54 and 138 months, respectively and one patient had local recurrence after...

" Precise tumor localization and exact delineation from surrounding healthy brain tissue is of the utmost importance for planning tumor resection and/or radiation therapy, as well as for assessment of tumor recurrence after primary therapy. " Approximately 1–2% of all tumors are brain tumors. Gliomas represent 45% of all brain tumors (50% being highly malignant), followed by meningiomas (27%), ...

Recently, matrix metalloproteinases (MMP), in particular the gelatinases MMP-2 and MMP-9, generally considered as tumor markers for clinical applications. A longitudinal 2-years follow-up survey was performed on dogs with cutaneous tumor. Serum samples were obtained from 22 dogs with different cutaneous tumors and 22 health dogs at the time of surgery and one month, three months and one year af...

Due to glioblastoma's infiltrative nature, an optimal radiation therapy (RT) plan requires targeting infiltration not identified by anatomical magnetic resonance imaging (MRI). Here, high-resolution, whole-brain spectroscopic MRI (sMRI) is used to describe tumor infiltration alongside anatomical MRI and simulate the degree to which it modifies RT target planning. In 11 patients with glioblastom...

the value of clinical use of tumor markers cea and ca15-3 for early detection of recurrent breast cancer still is a controversial. this study was investigated relationship between tumor markers cea and ca15-3 and recurrence breast cancer. data regarding 147 women who had breast cancer were entered into the study. patients were reviewed for 120 months after treatment. maximum time for relapse wa...