OBJECTIVES The aim of this study was to determine the effect of transient myocardial ischemia on circulating natriuretic peptide levels. BACKGROUND Natriuretic peptides are released by the heart in response to wall stress. We hypothesized that transient myocardial ischemia would cause acute changes in circulating natriuretic peptide levels. METHODS B-type natriuretic peptide (BNP), N-termin...

In contrast to the wealth of information available concerning the response of plasma atrial natriuretic peptide to changes in pressure and volume status and to inhibition of endopeptidase 24.11, very little is known of possible concomitant effects on brain natriuretic peptide. The effects of change in posture, pressor infusions of angiotensin II, or inhibition of endopeptidase 24.11 were docume...

Background. Increased levels of brain natriuretic peptide (BNP) and the N-terminal fragment (NT-proBNP) in heart failure (HF) indicates atrial ventricular myocardial remodeling. BNP NT- proBNP have great prognostic value patients with HF. However, fibrillation (AF) can affect interpretation NT-proBNP. AF is one most common conditions HF assessing predictive NT-proBNP extremely important clinica...

UNLABELLED There has been a large confirmation over the last decades that stroke may produce cardiac changes (echocardiographic, electrocardiographic, enzymatic). In ischemic stroke, systolic dysfunction is associated with a high risk of mortality during hospitalization. A recent study demonstrated that cardiac diastolic dysfunction could also accompany acute stroke besides the systolic dysfunc...

BACKGROUND Few data are available on diastolic function in patients with aortic stenosis (AOS) with indication of surgical treatment. A potential correlation between biomarkers and diastolic function has not been established. OBJECTIVE The aim of our study was to evaluate diastolic function in patients with AOS waiting for aortic valve replacement (AVR) echocardiographically, and to verify it...

colleagues evaluated brain natriuretic peptide (BNP) and N-terminal prohormone brain natriuretic peptide (NT-proBNP) serial measurements as predictive of 30-day and 1-year mortality and readmission in patients admitted to the emergency department for acute decompen sated heart failure (ADHF) [1]. Th e usefulness of measuring BNP and NT-proBNP in the diagnosis and management of congestive heart ...

BACKGROUND B-type natriuretic peptide (BNP) is a marker for ventricular dysfunction secreted as a pre-prohormone, pro-B-type natriuretic peptide (proBNP), and cleaved into BNP and a biologically inactive fragment, N-terminal pro-B-type natriuretic peptide (NT-proBNP). Little is known about the clinical usefulness of NT-proBNP in preterm infants. OBJECTIVE To evaluate the usefulness of plasma ...

BACKGROUND Atrial fibrillation (AF) is the most common cardiac arrhythmia with a population prevalence of about 1%. Natriuretic peptide level is elevated in patients with AF with diastolic dysfunction even with a normal left ventricular (LV) ejection fraction. The N-terminal pro-brain natriuretic peptide (NT-proBNP) level and Doppler echocardiographic parameters for diastolic function have show...