نتایج جستجو برای: brain inflammation

تعداد نتایج: 633631  

Journal: :Developmental Medicine & Child Neurology 2008

Journal: :Journal of Trauma and Acute Care Surgery 2015

Journal: :International journal of clinical and experimental medicine 2015
An Wu Rongcai Liu Weimin Dai Yuanqing Jie Guofeng Yu Xiaofeng Fan Qiang Huang

Early brain injury (EBI), following subarachnoid hemorrhage (SAH), includes blood-brain barrier (BBB) disruption and consequent edema formation. This study aims to evaluate the effect of lycopene on early brain injury and inflammation in SAH. Neurological deficits, brain water content and Evans blue dye extravasation were evaluated after the treatment with lycopene. Besides neuronal apoptosis,s...

Journal: :Molecular therapy : the journal of the American Society of Gene Therapy 2011
Xiaoying Zhuang Xiaoyu Xiang William Grizzle Dongmei Sun Shuangqin Zhang Robert C Axtell Songwen Ju Jiangyao Mu Lifeng Zhang Lawrence Steinman Donald Miller Huang-Ge Zhang

In this study, exosomes used to encapsulate curcumin (Exo-cur) or a signal transducer and activator of transcription 3 (Stat3) inhibitor, i.e., JSI124 (Exo-JSI124) were delivered noninvasively to microglia cells via an intranasal route. The results generated from three inflammation-mediated disease models, i.e., a lipopolysaccharide (LPS)-induced brain inflammation model, experimental autoimmun...

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