We compared the plasma antioxidants level of normal control group with that of hypertensive patients in order to test the hypothesis "that antioxidants level has been diminished in hypertensive patients and that antioxidants are interconnected with each other making a network. The plasma and red blood cells antioxidants level of newly diagnosed hypertensive patients [(n=30), (mean age 53 years)...

background & aim: free radicals are produced in ischemic processes. nerve damage caused by free radicals may play a role in neurological diseases and antioxidants are protective activity. ellagic acid is a polyphenol compound with antioxidant properties which is found in fruits like pomegranate, blackberry, and all types of mulberry. this study aimed to evaluate the effect of 14 days of ora...

Background: Free radicals in excessive concentrations damages cells and accelerate the aging process. Antioxidants found Centella asiatica (CA) Acalypha indica (AI) have potential to prevent oxidative cellular damage.
 Objective: This study aimed determine effect of CA AI on carbonyl glutathione levels brain older rats.
 Methods: 18-month age rats were treated using either AI, CA, or ...

Sepsis often is characterized by an acute brain dysfunction, which is associated with increased morbidity and mortality. Its pathophysiology is highly complex, resulting from both inflammatory and noninflammatory processes, which may induce significant alterations in vulnerable areas of the brain. Important mechanisms include excessive microglial activation, impaired cerebral perfusion, blood-b...

The significance of dietary antioxidants may be limited by the ability of animals to exploit them. However, past studies have focused on the effects of dietary antioxidants after 'antioxidant forced-feeding', and have overlooked spontaneous antioxidant intake. Here, we found that reproducing female Bicyclus anynana butterflies had higher antioxidant defences and enhanced fecundity when forced t...

Antioxidants are used on a very large scale to try to obtain and preserve optimal health. Nutraceuticals and food supplements frequently contain huge dosages of antioxidants. It is not generally recognised that high intake of antioxidants may also have adverse effects. Three antioxidants i.e. vitamin E, β-carotene and lipoic acid are used to illustrate general considerations on the toxicity of ...

glycation is a protein modification, which results in a change in a protein structure. glycation is believed to be the etiology of various age-related diseases such as diabetes mellitus and alz-heimer’s disease (ad). activation of microglia and resident macrophages in the brain by glycated proteins with subsequent oxidative stress and cytokine release may be an important factor in the progressi...