Type 2 diabetes mellitus is associated with increased inflammation and accelerated atherosclerosis. The association of the pro-inflammatory and potentially pro-atherosclerotic molecule, pregnancy associated plasma protein-A (PAPP-A) with diabetes and vascular diseases remains to be further established. A total of 107 patients with type 2 diabetes and 101 healthy controls participated in this st...

SEcOndhAnd SMOkE Parental Smoking May Set up children for Atherosclerosis Children frequently exposed to secondhand tobacco smoke may be at greater risk of developing athero sclerosis as adults, suggests new research published in the March 2010 issue of Circulation: Cardiovascular Quality and Outcomes. “Passive smoking has been associated with an increased risk of atherosclerosis in adults by a...

The aims of this study are to describe the mean values of carotid intima-media thickness and how it increases with age, and to compare carotid injury in diabetics and hypertensive patients with that of controls. We included 562 subjects (121 diabetics, 352 hypertensive patients, 89 controls). The mean intima-media thickness was 0.781 mm in diabetics, 0.738 mm in hypertensive patients and 0.686 ...

OBJECTIVE To describe and test a practical protocol to measure common carotid intima-media thickness that uses the combined values of two longitudinal examination angles to increase sensitivity. METHOD Between February and September 2005, 206 patients underwent duplex scan examination of carotid vessels, and the intima-media thickness of 407 common carotids were measured in three angles: tran...

B-mode ultrasound of Common Carotid artery at its bifurcation for measure of the Carotid intima-media thickness (CIMT), offers a valid non-invasive quantifying test for macro-vascular complications like atherosclerosis. Material and Methods: 50 cases of type 2 Diabetes and 30 age and sex matched Non-diabetics controls were taken for present study and subjected to Ultra-sonographic scanning of t...

INTRODUCTION The aim of the study was to assess carotid intima-media thickness (CIMT) as a subclinical marker of atherosclerosis and arterial stiffness in type 1 diabetic patients in relation to microangiopathy. MATERIAL AND METHODS We included 87 type 1 diabetic patients (44 women, 43 men), median age 34 years (interquartile range [IQR] 29-43), median disease duration 10 years (IQR: 9-14), m...

The authors studied associations between ankle-brachial index (ABI) and subclinical atherosclerosis in the Multi-Ethnic Study of Atherosclerosis. Participants included 3,458 women (average age = 62.6 years) and 3,112 men (average age = 62.8 years) who were free of clinically evident cardiovascular disease. Measurements included ABI, carotid artery intima-media thickness, and coronary artery cal...

OBJECTIVE Chemerin is a novel adipokine that is correlated with adipocyte differentiation, glucose metabolism, and inflammation. We aimed to investigate the relation between serum chemerin level and subclinical atherosclerosis markers as exemplified by brachial artery pulse wave velocity (baPWV), carotid intima-media thickness (CIMT), epicardial fat thickness (EFT), and carotid plaque presence ...

BACKGROUND Menopausal transition is critical for the development of early, subclinical vascular damage. Multiple factors, such as atherosclerosis, increased epicardial fat, and endothelial dysfunction can play a role. Hence, the objective of this study was the comparison of epicardial adipose tissue and carotid intima media thickness in order to establish the best predictor of carotid stiffness...

background: role of atherosclerosis  in the pathogenesis of ischemic and hemorrhagic  infarctions is still matter  of debate. intima-media thickness (imt) of the common carotid  artery (cca) and  internal  carotid  artery (ica) are markers of atherosclerosis. the aim of this study was to compare  cca imt and ica imt of patients  with ischemic and hemorrhagic infarction. methods: two equal group...