The sensitization of herpes simplex virus by immunoglobulin G (IgG) antibodies was studied. Although herpes simplex virus sensitized by IgG could not be neutralized by IgA antibodies known to neutralize a similar number of unsensitized viruses, this protection could be overcome by larger amounts of IgA antibodies. This suggests that the effective neutralization of herpes simplex virus in ocular...

An avidin-biotin complex system was compared with three commercially available immunofluorescence kits for serotyping herpes simplex virus isolates from clinical specimens. Sensitivity values showed that the Electro-Nucleonics and Immulok reagents were useful in detecting the presence of virus, whereas the predictive values showed that the Syva and Immulok reagents possessed adequate discrimina...

OBJECTIVE To determine the prevalence of herpes viruses in the semen of an asymptomatic male cohort with and without infertility problems and its association with altered semen parameters. DESIGN A prospective randomized study. SETTING Medical school and IVF clinic. PATIENT(S) One hundred seventy-two male patients undergoing routine semen analysis: 80 with normal semen parameters (control...

OBJECTIVE The purpose of this study was to determine the cost-effectiveness of routine antenatal screening for herpes simplex virus 1 and 2 in women without a known history of genital herpes. STUDY DESIGN Decision analysis was used to compare 3 treatment strategies to prevent neonatal herpes infection in women without a known history of genital herpes simplex virus: (1) the current standard o...

It has been proposed that intervertebral disc degeneration might be caused by low-grade infection. The purpose of the present study was to assess the incidence of herpes viruses in intervertebral disc specimens from patients with lumbar disc herniation. A polymerase chain reaction based assay was applied to screen for the DNA of eight different herpes viruses in 16 patients and two controls. DN...

Comparison of microbicides for efficacy in protecting mice against vaginal challenge with herpes simplex virus type 2, cytotoxicity, antibacterial properties, and sperm immobilization. Candidate microbicide PPCM blocks human immunodeficiency virus type 1 infection in cell and tissue cultures and prevents genital herpes in a murine model. ACIDFORM inactivates herpes simplex virus and prevents ge...

Herpes Zoster is caused by the Varicella virus, characterized a unilateral vesicular rash, usually restricted to specific dermatome.

the purpose of this study was to determine the prevalence of bovine leukemia virus (blv) in khorasan razavi and khorasan shomali provinces which are the main provinces located in the northeast of iran. total number of 429 blood samples were collected from industrial dairy herds. the samples were categorized based on province, age (2-3, 4-6, and 7-10 years old), calving (≤ 2, 3-5, and > 5) and h...

This topic will review the pathogenesis, epidemiology, risk factors for, clinical features, diagnosis, and treatment of VZV vasculopathy. The major clinical manifestations and complications of chickenpox and herpes zoster are discussed separately. (See "Epidemiology of varicella-zoster virus infection: Chickenpox" and "Treatment of varicella-zoster virus infection: Chickenpox" and "Vaccination ...

Herpes simplex virus type-1 (HSV-1) amplicon vectors are versatile and useful tools for transferring genes into cells that are capable of stimulating a specific immune response to their expressed antigens. In this work, two HSV-1-derived amplicon vectors were generated. One of these expressed the full-length glycoprotein D (gD) of bovine herpesvirus 1 while the second expressed the truncated fo...