Background: Boron Neutron Capture Therapy (BNCT) is an emerging radiotherapy. There are ongoing efforts to develop a Canadian accelerator-based BNCT center. However, it remains unclear how radiation oncologists (RO), medical physicists (MP), and their trainees perceive its impact on oncology as discipline. Methods: A survey was created explore the knowledge of BNCT, clinical role, support for r...

Boron carbide (B4C) is very hard, but its applications are hindered by stress-induced amorphous band formation. To explain this behavior, we used density function theory (Perdew-Burke-Ernzerhof flavor) to examine the response to shear along 11 plausible slip systems. We found that the (0111)/<1101> slip system has the lowest shear strength (consistent with previous experimental studies) and tha...

BACKGROUND Boron neutron capture therapy (BNCT) is a selective radiotherapy that is dependent on the accumulation of ¹⁰B compound in tumors. Low-intensity ultrasound produces a transient pore on cell membranes, sonoporation, which enables extracellular materials to enter cells. The effect of sonoporation on BNCT was examined in oral squamous cell carcinoma (SCC) xenografts in nude mice. MATER...

Since 1990, Boron Neutron Capture Therapy (BNCT) has been used for over 400 cancer patients at the Kyoto University Research Reactor Institute (KURRI). After BNCT, the patients are radioactive and their (24)Na and (38)Cl levels can be detected via a Na-I scintillation counter. This activity is predominantly due to (24)Na, which has a half-life of 14.96 h and thus remains in the body for extende...

The synthesis of boron subphthalocyanines (BsubPc) from modified phthalonitriles is reported. The BsubPcs have intense red-shifted absorption compared to normal BsubPcs and readily tuneable optoelectronic properties including enhanced electrochemical stability and the presence of up to two reversible electrochemical reductions.

The purpose of this study is to synthesize new boron containing carrier compound for Boron Neutron Capture Therapy (BNCT) which two-component radiation therapy method that especially promising the treatment brain tumors and being actively researched in many countries. For research hyperbranched polyester (HBP), bifunctional p-carborane carborane-functionalized HBP were synthesized. Dipentaeryth...

The values of the parameters used in boron neutron capture therapy (BNCT) to calculate a given dose to human tissue vary with patients due to different physical, biological and/or medical circumstances. Parameters include the tissue dimensions, the 10B concentration and the relative biological effectiveness (RBE) factors for the different dose components associated with BNCT. Because there is s...