©2005 British Editorial Society of Bone and Joint Surgery doi:10.1302/0301-620X.87B5. 16021 $2.00 J Bone Joint Surg [Br] 2005;87-B:608-17. The management of skeletal metastatic disease has attracted increasing attention during the past decade. In orthopaedic practice there is an increased demand for reconstructive surgery for both pathological fractures and in the management of paraplegia from ...

Radiofrequency ablation (RFA) for thoracic tumours has emerged as a minimally invasive therapy option for primary and secondary lung tumours and has gained increasing acceptance for pain palliation. The procedure is well tolerated and the complication rates are low. RFA provides the opportunity for localized tissue destruction of limited tumour volumes with medium and long term follow-up data s...

Radionuclide therapy is widely used as an effective modality in the management of bone pain. The main indication for this treatment is symptomatic bone metastases, confirmed by bone scintigraphy. We present a case of small cell lung cancer (SCLC) stage T4N2M1b, with a good metabolic response to systemic therapy and radiotherapy of the primary tumor and locoregional disease, which became metabol...

Two consecutive female patients presented with progressive jaundice, epigastric pain and weight loss. Cross-sectional imaging with computer tomography and magnetic resonance imaging did not show any mass lesions whereas magnetic resonance cholangiopancreatography showed common bile duct strictures. Both patients were then referred for endosonographic evaluation. Endoscopic ultrasound showed occ...

Pancreatic cancer is devastating due to its poor prognosis. Patients require a multidisciplinary approach to guide available options, mostly palliative because of advanced disease at presentation. Palliation including relief of biliary obstruction, gastric outlet obstruction, and cancer-related pain has become the focus in patients whose cancer is determined to be unresectable. Endoscopic stent...