Abstract- Production of gelatin from the aquatic source is gradually replacing mammalian sources because some socio-cultural and religious issues. The Pangasius pangasius catfish a native species very popular in Bangladesh due to their availability cheap price. perspective this study was extract skin bones compare them with commercial gelatin. Gelatin extracted by applying acid-base extraction ...

We studied the potential of polymeric cryogel matrices such as 2-hydroxyethyl methacrylate (HEMA)-agarose (HA) and gelatin matrix as a transporting and storage material for mammalian cells. Both the HA and gelatin matrices were found to possess a homogenous distribution of pores as shown by scanning electron microscopic (SEM) images and flow rate of 8 and 5 mL/min, respectively. In the case of ...

With the exception of small amounts in elastin, all the hydroxyproline (OHPr) in the body is found in collagen. Evidence has been presented that the urinary peptide-bound OHPr reflects the metabolism of collagen (2-5) except when the dietary intake of gelatin or collagen is excessive. Since a major body depot of collagen is the matrix of bone, it might be anticipated that under some conditions ...

Macrophages play an important role in regulating inflammatory responses and tissue regeneration. In the present study, their effect on bone remodeling is investigated by the simultaneous application of a macrophage recruiting agent, SEW2871 of a sphingosine-1 phosphate agonist, and platelet-rich plasma (PRP). The non-water soluble SEW2871 was solubilized in water through micelles formation with...

The present work describes for the first time the production of self-supporting low gelatin density (<10 w/v%) porous scaffolds using methacrylamide-modified gelatin as an extracellular matrix mimicking component. As porous scaffolds starting from low gelatin concentrations cannot be realized with the conventional additive manufacturing techniques in the abscence of additives, we applied an ind...

Matrilysin (PUMP, MMP-7) is a member of the metalloprotease gene family, whose constituents are responsible for the remodeling of extracellular matrix. The matrilysin protein is a 28-kDa zymogen possessing catalytic activities against a broad range of extracellular matrix substrates including proteoglycans, gelatin, fibronectin, laminin, and elastin. To gain insights into the biological express...

For tissue engineered bone constructs, calcium phosphate cement (CPC) has a high potential as scaffold material because of its biocompatibility and osteoconductivity. However, in vivo resorption and tissue ingrowth is slow. To address these issues, microspheres can be incorporated into the cement, which will create macroporosity after in situ degradation. The goal of this study was to investiga...

The objective of this study is to develop an osteoinductive scaffold which enables the controlled release of bone morphogenetic protein (BMP)-2. A biodegradable gelatin sponge incorporating 50 wt% of btricalcium phosphate (β-TCP) was fabricated to investigate the osteoinduction activity. The sponge prepared had an interconnected pore structure with an average pore size of 200 mm. The in vivo re...