Salivary gland related bone defects or Stafne bone defects are asymptomatic bone cavities in the mandible caused by impingement by the salivary glandular tissue. All the three major salivary glands are in approximation with the mandible and depressions with each can produce radiolucent defects on the surface of the mandible. These bone defects or depressions are categorized as anterior lingual ...

To identify cells with potential antileukemia activity following bone marrow transplantation. we have monitored immunologic reconstitution in a patient with acute lymphocytic leukemia in second remission who received intensive chemotherapy and total body irradiation followed by infusion of albogeneic histocompatible marrow. Prior to transplantation. donor bone marrow cells were depleted of T ly...

Bone metastasis is a common complication in prostate cancer patients that can cause bone pain and pathological fracture. This study tested serum levels of prostate specific antigen (PSA), alkaline phosphatase (ALP), bone sialoprotein (BSP), collagen type I pyridine crosslinking peptide (ICTP) in prostate cancer patients and the significance of the receiver operator characteristic (ROC) curve in...

introduction: aneurysmal bone cysts (abc) are extremely rare in the head and neck region and even rarer in sinuses.  abc is a benign multicystic mass that is locally-destructive and rapidly expandable. hemorrhagic fluid content (like in this case) and septated appearance are the characteristic feature of abc. established treatment options for abcs include sclerotherapy, embolization, radiothera...

Osteoporosis is a common metabolic skeletal disorder characterized by decreased bone mass and deteriorated bone structure, leading to increased susceptibility to fractures. With aging population, osteoporotic fractures are of global health and socioeconomic importance. The three-dimensional microstructural information of the common osteoporosis-related fracture sites, including vertebra, femora...

The initiation of cartilage degeneration has been linked to the onset of subchondral bone remodelling and osteophyte formation at the cartilage-bone interface. As such, Osteoarthritis (OA) is defined as the thinning of cartilage and/or osteophyte formation. Cartilage adjacent to healthy bone has a characteristic stress distribution when loaded within a healthy range. This loading is then transf...

Bone tissue engineering scaffolds should be designed to optimize mass transport, cell migration, and mechanical integrity to facilitate and enhance new bone growth. Although many scaffold parameters could be modified to fulfill these requirements, pore size is an important scaffold characteristic that can be rigorously controlled with indirect solid freeform fabrication. We explored the effect ...

Autologous bone marrow transplants for solid tumor treatment are severely limited by the potential presence of residual cancer cells in the reinfused bone marrow and can lead to future tumor recurrence. This article presents a novel method of removing carcinoma cells from bone marrow with contaminating cancer cells. This method is based on our previous studies demonstrating that carcinoma cells...

This present report concerns an infantile patient with mucolipidosis II, who showed transient cortical bone hyperostosis followed by severe osteopenia. The diagnosis of mucolipidosis II was made based on the leakage of lysosomal enzymes in serum and conditioned media of the patient's skin fibroblasts, low activity of lysosomal enzymes of the fibroblasts and mutation of c.2086_2089insC (p.L697fs...

OBJECTIVE Na(18)F bone positron emission tomography (bone PET) is a new imaging modality which is useful for the evaluation of bone diseases. Here, we compared the diagnostic accuracies between bone PET and bone scan for the detection of bone metastasis (BM). MATERIALS AND METHODS Sixteen cancer patients (M:F = 10:6, mean age = 60 ± 12 years) who underwent both bone PET and bone scan were ana...