Use of amphotericin B-impregnated bone cement in combination with systemic antifungals for the treatment of coccidioidal osteomyelitis offers the potential for sustained local concentrations of drug at the site of the infection. Amphotericin B levels in bone of up to 5.1 μg/g have been demonstrated 4 months after placement of bone cement.

Bone tunnel healing is an important consideration after anterior cruciate ligament (ACL) replacement surgery. Recently, a variety of materials have been proposed for improving this healing process, including autologous bone tissue, cells, artificial proteins, and calcium salts. Amongst these materials are calcium phosphates (CaPs), which are known for their biocompatibility and are widely comme...

Introduction Cement is the most abundantly used man made material on the planet, accounting for a 40 Billion USD market in the US alone [1]. Widespread use of cement includes applications in oil well casings, roadways, buildings, and even as a bone graft technology for the treatment of osteoporosis[2,3]. As cements role as the foundation of our infrastructure broadens, demand for higher strengt...

First generation glass ionomer bone cement was introduced by Wilson and Kent in 1970s and used in dental procedures . In 1989 Hehl et al. reported their experiences of fixing incudostapedial joint with glass ionomer cement . After this study many authors have presented their glass ionomer bone cement ossiculoplasty series [3,5] They showed that very satisfactory hearing improvements can be obta...

This study compared the mechanical strength of commercially prepared antibiotic bone cement (Simplex With Tobramycin; Stryker, Mahwah, NJ), cement with generic tobramycin (Pharma-Tek, Huntington, NY) blended in by the orthopedic nursing staff, and standard nonantibiotic bone cement. The results showed an approximate 36% decrease in the strength of the cement with hand-mixed generic tobramycin, ...

Aims Bone defects caused by bone loss due to trauma or tumours are common, with grafting of transplanted tissue currently as the gold standard for bone replacement. However, there are many issues inherent with autograft, including donor site morbidity, supply of tissue and infection [1]. In order to overcome these drawbacks, a diverse array of synthetic biomaterials is under development [2]. Ca...

We have synthesized calcium phosphate cements doped with different amounts of magnesium (Mg-CPC) with a twofold purpose: i) to evaluate in vitro the osteoblast cell response to this material, and ii) to compare the bone regeneration capacity of the doped material with a calcium cement prepared without magnesium (CPC). Cell proliferation and in vivo response increased in the Mg-CPCs in compariso...

Asphalt has been modified for the past several decades using various additives, including synthetic polymers. Polymer modification improves structural and engineering characteristics of the binder, which is a result of improvement in rheological characteristics of binder as well as its adhesion capability with the aggregate. Such enhancement inevitably enhances the performance characteristics o...

This study investigated experimentally the fracture properties, i.e., the fatigue strength, the resistance to crack propagation and the fracture toughness, of an acrylic bone cement (Cemex RX). The mean endurance limit was determined following the staircase method. The endurance limit was estimated at 9.2 MPa. The fatigue crack propagation rate was measured according to the ASTM E647 standard. ...

BACKGROUND Classic self-curing temporary cements obstruct the translucence of provisional restorations. New dual-cure esthetic temporary cements need investigation and comparison with classic cements to ensure that they are equally retentive and provide adequate translucence. The objective is to analyze by means of traction testing in a in vitro study the retention of five temporary cements. ...