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PURPOSE Improving hydration is a strategy commonly used by clinicians to prevent overeating with the goal of promoting a healthy weight among patients. The relationship between weight status and hydration, however, is unclear. Our objective was to assess the relationship between inadequate hydration and BMI and inadequate hydration and obesity among adults in the United States. METHODS Our st...
Methods Ninety patients (84 men, age 54.4±10.8y, BMI 27.8±4.5 kg/m) with acute (n=30), subacute (n=30) and chronic (n=30) myocardial infarction were included in the study. All imaging was performed on a 1.5-T clinical MR system (Achieva, Philips Medical Systems, Best, the Netherlands). Spatial resolution was identical for 3D and 2D images (1.5 x 1.5 mm, slice thickness 8 mm, no slice gap). Imag...
Results The proportions of patients with STEMI by BMI category were as follows: underweight (BMI 18.5 kg/m) 1.6%, normal weight (18.5 kg/m BMI 25 kg/m) 23.5%, overweight (25 kg/m BMI 30 kg/m) 38.7%, class I obese (30 kg/m BMI 35 kg/m) 22.4%, class II obese (35 kg/m BMI 40 kg/m) 8.7%, and class III obese 5.1%. Extreme obesity was associated with younger age at STEMI presentation (median age 55 y...
Obesity increases a person's susceptibility to a variety of infections, including Staphylococcus aureus infections, which is an important cause of morbidity in correctional settings. Using a cross-sectional design, we assessed the association between obesity and S. aureus colonization, a risk factor for subsequent infection, in New York State maximum-security prisons (2011-2013). Anterior nares...
Abstract Background Height, weight, and body mass index (BMI) are well established risk factors for atrial fibrillation (AF) but whether they also predictors of successful pharmacological cardioversion AF is unknown. Data from the open-label INSTANT study flecainide acetate oral inhalation solution (FlecIH) acute recent-onset symptomatic were examined to determine if these anthropometric measur...
INTRODUCTION Two thirds of United States adults are overweight or obese, which puts them at higher risk of developing chronic diseases and of death compared with normal-weight individuals. However, recent studies have found that overweight and obesity by themselves may be protective in some contexts, such as hospitalization in an intensive care unit (ICU). Our objective was to determine the rel...
BACKGROUND AND OBJECTIVES To report the prevalence of obesity in a Spanish working population and its changes in recent years. MATERIAL AND METHODS Data were collected from routine medical examinations performed on workers by a national mutual insurance society for occupational accidents and diseases (Ibermutuamur). A structured questionnaire was completed and physical examinations were perfo...
Acetyl coenzyme A carboxylase B gene (ACACB) single nucleotide polymorphism (SNP) rs2268388 is reproducibly associated with type 2 diabetes (T2DM)-associated nephropathy (DN). ACACB knock-out mice are also protected from obesity. This study assessed relationships between rs2268388, body mass index (BMI) and gene expression in multiple populations, with and without T2DM. Among subjects without T...
RESULTSdIn a sample of 20,985 type 1 diabetic patients (mean age, 38.6 years; mean BMI, 25.0 kg/m), 635 patients were hospitalized with HF as a primary or secondary diagnosis during a median follow-up of 9.1 years. Cox regression adjusting for age, sex, diabetes duration, smoking, HbA1c, systolic and diastolic blood pressures, and baseline and intercurrent comorbidities (including myocardial in...
OBJECTIVE We investigated the effects of 18 confirmed type 2 diabetes risk single nucleotide polymorphisms (SNPs) on insulin sensitivity, insulin secretion, and conversion of proinsulin to insulin. RESEARCH DESIGN AND METHODS A total of 5,327 nondiabetic men (age 58 +/- 7 years, BMI 27.0 +/- 3.8 kg/m(2)) from a large population-based cohort were included. Oral glucose tolerance tests and geno...
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