This study was conducted to evaluate canine parvovirus disease prevention efficacy of the minimum immunizing dose of the CPV-2b fraction of a multivalent vaccine when administered at approximately 6 weeks of age to pups with maternal CPV-2b antibodies. A second dose was administered 4 weeks later. Pups were challenged with a virulent strain of CPV-2c virus 2 months after the second vaccination....

Intestinal parasites cause significant morbidity and mortality. Diseases caused by Enterobius vermicularis, Giardia lamblia, Ar^cylostoma duodenale, Necator americanus, and Entamoeba histolytica occur in the United States. E. vermicularis, or pinworm, causes irritation and sleep disturbances. Diagnosis can be made using the "cellophane tape test." Treatment includes mebendazole and household sa...

Escherichia coli O157:H7 causes bloody diarrhea and potentially fatal systemic sequelae in humans. Cattle are most frequently identified as the primary source of infection, and E. coli O157:H7 generally colonizes the gastrointestinal tracts of cattle without causing disease. In this study, persistence and tropism were assessed for four different E. coli O157:H7 strains. Experimentally infected ...

In January 2001, a cluster of 24 cases of salmonellosis was investigated by the Communicable Disease Control Branch, Department of Human Services, South Australia. Hypothesis generating interviews sought demographic, illness, food purchasing practices, food consumption, social activities, and animal contact information for the 7 day period prior to the onset of symptoms. Eight (7 female, 1 male...

3. Madanagopalan N, Vedachalam SP, Subramaniam R, Murugesan RG. Rectal and colonic mucosal biopsy fi ndings and faeces, sigmoidoscopy, and histopathological correlation in amoebiasis and other colitis. Gut 1968; 9:106-110. REFERENCES A 61-year-old Bristish woman, had history of visiting Far East for years, presented with abdominal cramping pain and bloody mucous diarrhea for 3 weeks. Examinatio...

BACKGROUND Imiquimod is a Toll-like receptor-7 agonist that regulates immunity and can be used as an immune adjuvant. Ulcerative colitis has a close correlation with immune disorder. AIM To investigate the therapeutic effect of imiquimod on dextran sulfate sodium (DSS)-induced colitis and explore the underlying mechanisms. METHODS C57BL/6J C57 mice received 3% DSS for 7 days to induce ulcer...

A 5-week-old male infant presented with a 1-week history of vomiting. His mother stated that the vomiting generally occurred soon after the infant was fed. Initially, the vomiting was infrequent but was progressively worsening. The patient’s mother reported that the infant had been feeding well and had a good appetite. However, he had begun vomiting the entire volume of formula shortly after be...

INTRODUCTION The incidence of gastrointestinal food allergy (FA) in neonates is increasing. Despite this, cases of patients with gastrointestinal FA who develop necrotizing enterocolitis (NEC) requiring laparotomy are extremely rare. PRESENTATION OF CASE We describe two cases that presented with bloody stool with a probable diagnosis of FA as eosinophils were positive in the stool at onset. B...

To determine the clinical and microbiologic features of Shigella and enteroinvasive Escherichia coli (EIEC) infections, we investigated 410 children with diarrhea and 410 control children without diarrhea who were seen at Children's Hospital, Bangkok, Thailand, from January to June 1985. Shigella spp. were isolated from 96 (23%) and EIEC were isolated from 17 (4%) of 410 children with diarrhea ...

Intestinal protozoa are one of the leading causes of waterborne outbreaks. Stool samples of 196 residents from a village of Izmir, using the public water supply, were collected during an outbreak of gastroenteritis. Patients were asked to fill out a questionnaire reporting on gender, age, gastrointestinal symptoms, whether or not there was a toilet in the house, their hygiene practices, and sim...