Our group has developed microfluidic in vitro devices that mimic the response of humans or animals to drugs, toxins, or nanoparticles. Each device, or cell culture analog (CCA), contains an array of pseudo tissues that are interconnected by microfluidic channels [1]. The recirculation of blood surrogate through the microchannels allows us to study tissuetissue interactions, such as the breakdow...

A model-based insulin sensitivity parameter (SI) is often used in glucose-insulin system models to define the glycaemic response to insulin. As a parameter identified from clinical data, insulin sensitivity can be affected by blood glucose (BG) sensor error and measurement timing error, which can subsequently impact analyses or glycaemic variability during control. This study assessed the impac...

Toxoplasma gondii is intracellular parasites, which infect a large proportion of the world ' s population, but uncommonly causes clinically significant disease .The present study was performed to estimate the prevalence of toxoplasmosis in Iraqi male. Venous blood samples were collected from healthy male age between (18-57) years attended the National blood transfusion centre in Baghdad from Oc...

Multiple longitudinal studies have demonstrated reasonable stability of blood pressure (BP) levels and hemodynamics throughout childhood and adolescence and into adulthood. Part of this stability might be caused by genetic factors that are expressed steadily over time. We aimed to determine the relative contributions of genetic and environmental factors to the stability of BP and underlying hem...

The pulse pressure variation (PPV) is a measure of the respiratory effect on the variation of systemic arterial blood pressure (ABP) in patients receiving full mechanical ventilation. It is a promising predictor of increases in cardiac output due to an infusion of fluid. We describe a novel automatic algorithm to estimate the PPV of ABP signals recorded under full respiratory support. The algor...

Background: Improvements in the biocompatibility of dialysis membranes have reduced biological responses elicited by blood–membrane interactions. In this article, recent technological developments in dialysis membranes with regard to biocompatibility and recent progress in the evaluation of the biocompatibility of dialysis membranes are reviewed. Summary: The focus of investigation into dialysi...

CASE #1: 80 year old female with a history of dypsnea on exertion (DOE) and syncope. Workup reveals aortic stenosis (AVA=0.8cm2) and normal coronary arteries by cardiac catheterization with moderate concentric hypertrophy and an EF of 50%. Her other PMH is unremarkable. She was advised by her cardiac surgeon to seek a preoperative anesthetic consultation because she joined the Watch Tower organ...

Biomedical investigations with small animals using 0.5-T and 7-T MRI scanners adjusted on the Larmor frequencies of different nuclei 1H, 2H, 11B, 13C, 19F, 23Na, 31P, 35Cl are described. Experiments on registration of signals 19F from the fluorocarbons injected in laboratory animals are discussed. They give presentation on the application of fluorocarbon compounds as blood substitutes and contr...