BackgroundWe evaluated the long-term outcomes of coronary artery bypass grafting (CABG) according to β-blocker therapy using landmark analysis. Although β-blockers have been shown improve for ischemic heart disease, effects and optimal treatment duration use after CABG remain unknown.MethodsFrom January 2001 December 2014, 5382 patients were stratified into 2 groups at discharge (β-blocker grou...

OBJECTIVES This study was designed to determine adherence to outpatient beta-blocker therapy following acute myocardial infarction (AMI). BACKGROUND The importance of beta-blocker therapy after AMI is widely recognized. Outpatient adherence with this recommendation, however, is not well described. METHODS Data on 846 patients surviving AMI were studied. Factors associated with filling a bet...

PURPOSE Studies suggest that beta-blockers improve outcomes in heart failure patients and may be cost saving to society. However, many heart failure patients are not treated with beta-blockers. Economic incentives facing hospitals, physicians, payers, and patients may not encourage treatment adoption. We assessed the economic effects of beta-blocker therapy from various perspectives: societal, ...

OBJECTIVES We compared the hemodynamic effects of dobutamine and enoximone administration before and after long-term beta-blocker therapy with metoprolol or carvedilol in patients with chronic heart failure (HF). BACKGROUND Patients with HF on beta-blocker therapy may need hemodynamic support with inotropic agents, and the hemodynamic response may be influenced by both the inotropic agent and t...

BackgroundGuideline-directed medical therapy (GDMT) reduces mortality in patients with heart failure reduced ejection fraction. However, GDMT is not uncommonly de-escalated following implanted cardioverter defibrillator (ICD) implantation. We describe our experience the Device Medical Optimization Clinic (DMOC) at Hamilton Health Sciences, which was established to facilitate optimization cardia...

The study was carried out on the current diversification of antihypertensive drugs prescribed for treatment hypertensive patients irrespective age and sex in Government Hospitals Khulna city, Bangladesh. covered only indoor patients. frequency hypertension found maximum with above 40 years age. showed that prevalence more common females compared to males. Among therapeutic classes, Calcium chan...

Non-cardiogenic pulmonary edema has not been previously described in calcium channel blocker overdose. We describe a case of non-cardiogenic pulmonary edema occurring during the course of therapy for massive diltiazem overdose in a young patient with anorexia nervosa. Review of the current literature suggests that major and minor pulmonary complications occur with some frequency in the setting ...

Background-—Patients with myocardial infarction (MI) and concomitant chronic obstructive pulmonary disease (COPD) constitute a high-risk group with increased mortality. b-Blocker therapy has been shown to reduce mortality, prevent arrhythmias, and delay heart failure development after an MI in broad populations. However, the effect of b-blockers in COPD patients is less well established and the...

Background-—Patients with myocardial infarction (MI) and concomitant chronic obstructive pulmonary disease (COPD) constitute a high-risk group with increased mortality. b-Blocker therapy has been shown to reduce mortality, prevent arrhythmias, and delay heart failure development after an MI in broad populations. However, the effect of b-blockers in COPD patients is less well established and the...