OBJECTIVE To study the demographic and clinical characteristics of patients with antiphospholipid syndrome (APS) with serious haemorrhagic complications of anticoagulant treatment in an attempt to establish risk factors for bleeding. METHODS Patients with APS who were attending our lupus unit and who presented with severe bleeding while receiving oral anticoagulation were studied retrospectiv...

The results of endoscopy in acute upper gastrointestinal haemorrhage were compared in a group of 138 Africans and one of 84 Europeans. Contrary to widely held clinical opinion, the incidence of gastric and duodenal ulceration was similar in the two races. Peptic ulcers were the main source of bleeding in both groups and were surprisingly more common than varices in the Africans. Bleeding from v...

The treatment of life-threatening post-partum haemorrhage (PPH) still remains challenging, and hysterectomy may be required to control the bleeding. We present 12 cases of severe PPH treated with recombinant factor VIIa (rFVIIa). We briefly describe the causes of the haemorrhage and the medical and surgical interventions before rVIIa administration. In 11 women there was a partial or good respo...

Surgical specimens taken from 14 patients with lobar intracerebral haemorrhage or cerebellar haemorrhage without vascular abnormalities on angiograms were examined histologically. In seven of the 14 patients, arteriovenous malformation or amyloid angiopathy were found by ordinary pathological examinations. Among the remaining seven patients, definite microaneurysms were verified in five and pos...

BACKGROUND Tonsillectomy is one of the most common procedures performed in ENT departments. The most common complication is a haemorrhage, which incidence is estimated at 3-3.9% of all procedures. CASE REPORT We present the case of a 32-year-old female with severe bleeding 11 and 23 days after tonsillectomy. An angiography revealed a pseudoaneurysm of the facial artery (FA), a 5 mm in diamete...

INTRODUCTION The authors present a potential complication associated with the surgical management of post-tonsillectomy haemorrhage using absorbable cellulose haemostatic dressings. The article discusses the deficiencies of our current understanding of how best to manage this common and potentially life-threatening ENT emergency. CASE REPORT A 40-year-old man presented to Accident-and-Emergen...

Every minute of every day, a woman dies in pregnancy or childbirth. The biggest killer is obstetric haemorrhage, the successful treatment of which is a challenge for both the developed and developing worlds. The presence of an attendant at every birth and access to emergency obstetric care are key to reducing maternal morbidity and mortality in the developing world while resource-rich countries...

Abstract Background Regardless of the cause superficial siderosis (SS) disease, which is bleeding, source bleeding cannot be found in some cases. Case presentation In this article, we report two cases with idiopathic SS. 1 presented bilateral hearing loss, cognitive impairment, sleep disturbances, and tremors. 2 sensory neural ataxia, spastic paraparesis. both cases, brain MRI indicated evidenc...

It has long been known that injury to the abdominal viscera may cause stillbirth or death in the first days of life. Information about bleeding from the abdominal viscera has been obtained largely from post-mortem examinations of stillborn babies and babies dying shortly after birth. The incidence of bleeding from the liver estimated in this way is shown in Table 1. Hepatic haemorrhage is, ther...

A 61-years-old male presented with emesis after some retching episodes. He had liver cirrhosis but no previous bleeding. An upper endoscopy revealed an extensive 10 cm tear involving the mucosa and submucosa layers of the distal esophagus sparing a 2 cm long segment proximal to the Z-line (Fig. 1). The laceration presented a slowly oozing haemorrhage that was stopped with the injection of 6 cc ...