BACKGROUND This study aimed to examine the level of knowledge, attitude, acceptance, and willingness to pay (WTP) for HPV vaccination among female parents of girls aged 12-15 years in Thailand. MATERIALS AND METHODS A cross-sectional survey was conducted in eight schools across Bangkok. RESULTS Of 1,200 questionnaires sent out, a total of 861 questionnaires were received. Knowledge regardin...

1. The molecular weight of the calcium-binding protein of rabbit white skeletal muscle was estimated to be 18500 by sedimentation equilibrium and electrophoresis in sodium dodecyl sulphate. 2. Addition of 2 Ca(2+) ions per molecule produced reversible changes in the u.v.-absorption spectrum that are interpreted as arising from conformational changes in the structure of the protein. 3. Cd(2+) wa...

Two fructose diphosphate aldolases (EC 4.1.2.13) were detected in extracts of Escherichia coli (Crookes' strain) grown on pyruvate or lactate. The two enzymes can be resolved by chromatography on DEAE-cellulose at pH7.5, or by gel filtration on Sephadex G-200, and both have been obtained in a pure state. One is a typical bacterial aldolase (class II) in that it is strongly inhibited by metal-ch...

OBJECTIVE To examine the effect of the bivalent human papillomavirus (HPV) vaccine on miscarriage. DESIGN Observational long term follow-up of a randomized, double blinded trial combined with an independent unvaccinated population based cohort. SETTING Single center study in Costa Rica. PARTICIPANTS 7466 women in the trial and 2836 women in the unvaccinated cohort enrolled at the end of t...

UNLABELLED Studies have demonstrated that the bivalent (111)In-labeled leukotriene B4 (LTB4) antagonist DPC11870 reveals infectious and inflammatory lesions in various rabbit models. The radioactive tracer accumulates quickly at the site of infection and clears rapidly from the circulation, resulting in high-quality images. In this study, 2 new hydrazinonicotinamide (HYNIC)-conjugated compounds...

The fluorescence of the cation auramine O was substantially enhanced by the presence of actin monomer. Titrations of this fluorescence enhancement indicated that actin monomer had two auramine O binding sites, each with a dissociation constant of approx. 20 microM. Calcium ions had no effect on the number of actin monomer-bound auramine O molecules or on the dissociation constant for that inter...

Proton–ligand association constants of imidazole-4-acetic acid (IMA) were determined potentiometrically in aqueous solution at different temperatures in the range 15–35 C. The stepwise stability constants of IMA with some selected bivalent transition metal ions were also determined in 0.1 mol dm NaNO3. The stability of the complexes follows the trend Cu [ Ni [ Co [ Mn, which is in agreement wit...

Aminopeptidase W is a newly discovered enzyme of the renal and intestinal brush borders, having been first isolated as a 130 kDa glycoprotein recognized by a monoclonal antibody [Gee & Kenny (1985) Biochem. J. 230, 753-764]. It is particularly effective in the hydrolysis of dipeptides, Glu-Trp (Km 0.57 mM; kcat. 6770 min-1) being a favoured substrate. Dipeptides with tryptophan, phenylalanine o...

Immunofertilization studies have shown that anti-sera have a number of effects on sea urchin eggs. An unusually interesting feature of the action of antibody on the fertilizing capacity of the eggs is the dependence on the bivalent character of the antibody. Treatment of the eggs with univalent antibody prepared by papain digestion has no effect on fertilizability (Metz and Thompson, 1967; Graz...

An acidic residue in transmembrane segment (TMS) 10 is important for recognition of bivalent cationic substrates by the QacA multidrug transporter. Remarkably, an acidic residue in TMS 12 compensated for the absence of such a residue in TMS 10, suggesting that TMS 12 is a component of the bivalent cation-binding region.