DTU has focused on Part 2 that gives the background for the new EFSA temporary TDI of 4 μg/kg bw/day. In addition, the overall conclusion with regards to risk assessment has been considered. DTU has not made a specific evaluation of the EFSA exposure assessment (i.e. Part 1). DTU has in September 2013 evaluated the EFSA draft exposure assessment and concluded the draft was of high quality and b...

Bisphenol A (BPA), 2,2-bis(4-hydroxyphenyl) propane, is one of the most utilized industrial chemicals worldwide, with the ability to interfere with/or mimic estrogenic hormones with associated biological responses. Environmental human exposure to this endocrine disruptor, mostly through oral intake, is considered a generalized phenomenon, particularly in developed countries. However, in the con...

OBJECTIVE To review the literature on bisphenol A (BPA) exposure and obesity in human populations. DESIGN Systematic review of the literature via searches of PubMed, EMBASE, Web of Science and reference lists for articles published to 1 August 2014. SETTING China, Italy, Japan, Republic of Korea, Sweden, UK, USA. SUBJECTS Adults (≥ 18 years). RESULTS Eighteen articles were identified an...

The preclinical evaluation of drugs, including environmental agents, depends on toxicology studies carried out in animals under defined in vivo and in vitro conditions. With the advancement of biological and analytical sciences, toxicology has become highly multidisciplinary involving cellular, biochemical and molecular technology. It is now mandatory to perform reproductive and genetic toxicol...

The Schiff base compounds N,N'-bis[(E)-quinoxalin-2-ylmethylidene]propane-1,3-diamine, C(21)H(18)N(6), (I), and N,N'-bis[(E)-quinoxalin-2-ylmethylidene]butane-1,4-diamine, C(22)H(20)N(6), (II), crystallize in the monoclinic crystal system. These molecules have crystallographically imposed symmetry. Compound (I) is located on a crystallographic twofold axis and (II) is located on an inversion ce...

Many phenols are known to mimic or antagonize hormonal activities and may adversely affect fetal growth. A study of 567 pregnant women was conducted to investigate the relationship between prenatal phenol exposure and birth outcomes, including birth weight, length, and gestational age. We measured the concentrations of bisphenol A, benzophenone-3, 4-n-octylphenol and 4-n-nonylphenol in maternal...

Executive Summary 1 Chapter 1: Introduction 4 Chapter 2: Bisphenol E Cyanate Ester/Multiwalled Carbon Nanotubes 8

This study reports a novel super-hydrophobic surface with fluorinated cross-linked poly[cyclotriphosphazene-co-(4,4'-(hexafluoroisopropylidene)diphenol)] microspheres prepared via a single-step precipitation polymerization and simple dip-coating route.

The homopolymerization and copolymerization of styrene and methyl methacrylate, initiated for the first time by the combination of azo-bis-isobutyronitrile (AIBN) with [(SiMes)Ru(PPh3)(Ind)Cl2] complex. The reactions were successfully carried out, on a large scale, in presence this complex at 80 °C. It was concluded from the data obtained that the association of AIBN with the ruthenium complex ...

The competitive adsorption of bisphenol A (BPA) and17α-ethinylestradiol (EE2) with different endocrine disrupting compounds (EDCs), such as estrone (E1), β-estradiol (E2), and estriol (E3) was investigated in the water-sediment system. The primary and interaction effects of coexisted EDCs on the adsorption of BPA and EE2 were studied in binary and multiple systems. The adsorption selectivity of...