Mammalian embryonic development is epigenetic in that hormonal signals control not only the timing of gene expression but set the activity of genes and thus the functioning of organs and homeostatic systems for the remainder of life (Newbold et al., 2004). Variation in endogenous hormones, such as estradiol and testosterone, which regulate development of organs (vom Saal, 1989), or disruption o...

Superoxide dismutase play important roles in iron-respiratory bacteria such as Geobacteraceae as an antioxidant defense, and probably an effective enzyme of electron transfer network. Regarding the application of iron-respiratory bacteria in environmental biotechnology particularly biodegradation and bioremediation, understanding the mechanism of inhibition/induction of superoxide dismutase by ...

Environmental exposures during sensitive windows of development can reprogram normal physiologic responses and alter disease susceptibility later in life in a process known as developmental reprogramming. For example, exposure to the xenoestrogen diethylstilbestrol during reproductive tract development can reprogram estrogenresponsive gene expression in themyometrium, resulting in hyperresponsi...

INTRODUCTION Treatment with fixed orthodontic appliances requires the application of adhesive systems to enable secure fastening of brackets and retainers to the surface of tooth enamel. The orthodontic bonding systems are similar in terms of chemical composition to dental filling materials, the chemical stability of which is not satisfactory. Particularly alarming is the release of bisphenol A...

This document is a summary statement of the outcome from he meeting: “Bisphenol A: An Examination of the Relevance of cological, In vitro and Laboratory Animal Studies for Assessng Risks to Human Health” sponsored by both the NIEHS and IDCR at NIH/DHHS, as well as the US-EPA and Commonweal n the estrogenic environmental chemical bisphenol A (BPA, ,2-bis(4-hydroxyphenyl)propane; CAS# 80-05-7). T...

Objectives: The aim of this study has been to evaluate the rate of contact sensitization to some rubber allergens and to bisphenol A (BPA) amongst students of dental medicine and dental patients. Material and Methods: A total of 50 participants were included in the study: 40 students of dental medicine exposed to the studied rubber allergens and BPA-based dental materials during the course of t...

The chromatographic method used to monitor the Bisphenol-A manufacturing process was improved using Agilent RRHT Eclipse XDB-C18 columns. These columns use 1.8-μm particles versus conventional 3.5-μm or 5-μm particles. The improved method allowed seven times faster analyses, improved resolution, and higher sensitivity. Introduction Bisphenol-A (Figure 1) is a highly versatile material used to m...