Introduction Treatment adherence in patients living with Bipolar Disorders can influence prognosis and quality of life. It is associated an increased morbidity healthcare costs. Objectives The aim our study was to evaluate treatment a sample disorders determine factors poor adherence. Methods We conducted cross sectional where we included bipolar being treated psychiatry department A. developed...

Bipolar disorders and substance use disorders (SUDs) show high co-occurrence. One explanation for this co-occurrence may be common personality vulnerabilities involved in both. The authors tested whether high behavioral approach system (BAS) sensitivity and impulsiveness are shared personality vulnerabilities in bipolar spectrum disorders and substance use problems and their co-occurrence in a ...

BACKGROUND Bipolar affective disorder has a high rate of comorbidity with a multitude of psychiatric disorders and medical conditions. Among all the potential comorbidities, co-existing anxiety disorders stand out due to their high prevalence. AIMS To determine the lifetime prevalence of comorbid anxiety disorders in bipolar affective disorder under the care of psychiatric services through sy...

There is an urgent need for biomarkers of bipolar disorder to optimize its treatment. Although inflammatory markers have been most established biomarkers of bipolar disorder, molecular basis of cytokine elevation is not known. We hypothesized that plasma mitochondrial DNA (mtDNA), one of mitochondrial damage-associated molecular patterns, would contribute to inflammation observed in bipolar dis...

BACKGROUND Impairments in cognitive functions are common in patients suffering from psychiatric disorders, such as schizophrenia and bipolar disorder. Cognitive traits have been proposed as useful for understanding the biological and genetic mechanisms implicated in cognitive function in healthy individuals and in the dysfunction observed in psychiatric disorders. METHODS Sets of genes associ...

There is an urgent need for biomarkers of bipolar disorder to optimize its treatment. Although inflammatory markers have been most established biomarkers of bipolar disorder, molecular basis of cytokine elevation is not known. We hypothesized that plasma mitochondrial DNA (mtDNA), one of mitochondrial damage-associated molecular patterns, would contribute to inflammation observed in bipolar dis...

OBJECTIVE Comorbid bipolar and panic disorders aggregate in families. A phenotypic trait shared by both disorders is the sudden shift in affect observed in panic attacks and some rapid cycling states. The authors investigated whether comorbidity of bipolar disorder and panic disorder is associated with rapid mood switching in families with a high rate of bipolar disorder. METHOD Six hundred s...

BACKGROUND Relapse and hospital admission are common among, and carry a heavy burden in, patients with schizophrenia and bipolar disorder. The aim of this study was to assess the risk of relapse and hospitalizations in patients with schizophrenia and bipolar disorder at the St Amanuel Mental Specialized Hospital, Addis Ababa, Ethiopia. PATIENTS AND METHODS A hospital-based comparative cross-s...