نتایج جستجو برای: biological safety

تعداد نتایج: 717230  

2017
M. S. Camacho-Lovillo A. Bulnes-Ramos W. Goycochea-Valdivia L. Fernández-Silveira E. Núñez-Cuadros O. Neth P. Pérez-Romero

BACKGROUND Seasonal influenza virus vaccination should be considered in all pediatric patients with rheumatic diseases. Few studies have addressed influenza vaccination safety and efficacy in this group. We aim to prospectively evaluate immunogenicity and safety of the trivalent inactivated influenza vaccine including A/H1N1, A/H3N2 and B strains in children with juvenile idiopathic arthritis (...

2017
Juyong Hong Yuhwa Lee Changsoo Lee Suhyeon Eo Soyeon Kim Nayoung Lee Jongmin Park Seungkyu Park Donghyuck Seo Min Jeong Youngji Lee Soojeong Yeon George Bou-Assaf Zoran Sosic Wei Zhang Orlando Jaquez

A biosimilar is a biological medicinal product that contains a version of the active substance of an already authorized original biological medicinal product. Biosimilarity to the reference product (RP) in terms of quality characteristics, such as physicochemical and biological properties, safety, and efficacy, based on a comprehensive comparability exercise needs to be established. SB2 (Flixab...

2013
Masanori Yamada Mikio Akita Tomofumi Nakagawa Naoki Takahashi Akira Endo Pascal Yoshida

OBJECTIVES Belimumab, an anti-B lymphocyte stimulator (BLyS) human monoclonal antibody, was approved in the United States, Canada and European Union for the treatment of the patients with systemic lupus erythematosus (SLE). However, belimumab had not been evaluated in Japanese patients. The objectives of this study were to evaluate the safety and tolerability of belimumab in Japanese patients w...

Journal: :iranian rehabilitation journal 0
morteza oostakhan department of environmental and occupational health engineering, faculty of medicine, tarbiat modares university, tehran, iran. shahram vosoughi department of health sciences, faculty of health, safety and environment, shahid beheshti university of medical sciences, tehran, iran. mohammad khandan department of ergonomics, university of social welfare and rehabilitation sciences, tehran, iran.

objectives: because of the high rates of accidents, the construction industry has become a hazardous industry in iran and therefore paying more attention is required. this paper investigates safety management in construction companies for improving workers’ safety as one of the ergonomics aims. methods: in order to survey the safety management in construction companies a questionnaire was prepa...

Journal: :journal of modern processes in manufacturing and production 2013
hadi shirooyezad negin berjis farimah mokhatab rafiei

occupational accidents severely deteriorate human capital, and hence negatively affect the productivity andcompetitiveness. but despite these negative points, there are still deficiencies in safety managementperformance and indicators. therefore the safety issue needs an active management. for this reason, thewriter has proposed an approach to evaluate organizations based on safety management. ...

2017
Ruth Y. Litovsky Matthew J. Goupell Alan Kan David M. Landsberger

A growing number of laboratories are using research interfaces to conduct experiments with cochlear-implant (CI) users. Because these interfaces bypass a subject's clinical sound processor, several concerns exist regarding safety and stimulation levels. Here we suggest best-practice approaches for how to safely and ethically perform this type of research and highlight areas of limited knowledge...

Journal: :Annals of the Rheumatic Diseases 2021

Background: Biological therapy in combination is discouraged the guidelines for treatment of immune-mediated inflammatory diseases, attending to safety reasons. However, combined biological could be a valid alternative patients with highly refractory spondyloarthritis (SpA) as has been previously demonstrated some reluctant bowel disease patients. Published experiences literature are very scarc...

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