نتایج جستجو برای: bioconjugate

تعداد نتایج: 260  

2012
Simon J. Attwood Anna M. C. Simpson Rachael Stone SamirW. Hamaia Debdulal Roy RichardW. Farndale Myriam Ouberai Mark E. Welland

Single molecule force spectroscopy is a technique that can be used to probe the interaction force between individual biomolecular species. We focus our attention on the tip and sample coupling chemistry, which is crucial to these experiments. We utilised a novel approach of mixed self-assembled monolayers of alkanethiols in conjunction with a heterobifunctional crosslinker. The effectiveness of...

Journal: :AppliedChem 2023

Novel SF5-bearing maleimide and acrylamide derivatives were synthesised as potential [18F]radio-prosthetic groups for radiolabelling peptides proteins. The efficacy of selected prosthetic was first assessed through bioconjugation with protected model amino acid derivatives. These reactions investigated on an analytical scale via LC-MS across a pH range to quantitatively evaluate this group’s re...

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