Background. Silver nanoparticles have found wider and increasing biomedical applications due to their broad antimicrobial characteristics. However, toxicity of nanoparticles is a subject of continued controversy, thus necessitating further studies in this direction. Objectives. This study investigated the biochemical effects of silver nanoparticles in Wistar rats. Materials and Methods. Forty m...

BACKGROUND Kratom (Mitragyna speciosa) is a tropical tree with a long history of traditional use in parts of Africa and Southeast Asia. Kratom is also known as Thom, Thang, and Biak. Its leaves and the teas brewed from them have long been used by people in that region to manage pain and opioid withdrawal and to stave off fatigue. Kratom is actually consumed throughout the world for its stimulan...

After the introduction of the automated cell coulters, the incidence of detecting macrocytosis have increased and has varied from 1.7 to 3.6% in several reported series. 1-4 Detectable macrocytosis may not be present in peripheral smear in about 33% of cases with MCV >100fl. 1 Mild increase in MCV (MCV of 100 – 110fl) is particularly common and most often remains unexplained though it cannot be...

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The aim of the present study was to investigate the toxicological effects of moxifloxacin in mice to determine the toxicological implications. Forty mice of both sexes were divided into four groups of 10 mice each, designated as A, B, C and D. Group A served as the control and received 2 ml of distilled water, while Groups B, C and D were orally administered 12.5, 25 and 50 mg/kg body weight of...

From the Department of Biochemistry, Gulhane Military Medical Academy School of Medicine, Ankara, Turkey; Department of Biochemistry, Agri Military Hospital, Agri, Turkey; Department of Biochemistry, Sirnak Military Hospital, Sirnak, Turkey Received: Jun. 21, 2014; Accepted: Nov. 06, 2014 Correspondence to: Asst. Prof. Yasemin Gulcan Kurt, Department of Biochemistry, Gulhane Military Medical Ac...

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The aim of this study was to compare the clinical and biochemical parameters in colic horses (n=20) with that of healthy control animals (n=10). Further, the measured parameters were also compared between survived and non-survived colic patients. Clinical parameters included were rectal temperature, respiration rate (RR), capillary refill time (CRT) and heart rate (HR). Biochemical parameters e...

Pseudoisocytidine (*ICyd) is a C-nucleoside with enhanced stability and resistance to enzymatic deamination when com pared to 5-azacytidine and 1-ß-D-arabinofuranosylcytosine. Elimination kinetics in plasma using [14C]^ICyd showed a ßphase fi/2 for 14C of 2 hr and a yS-phase f,/2 of unchanged ¥ICyd of 1.5 hr. Net recovery of radioactivity in urine over 24 hr varied between 40 and 80% of the ...