BACKGROUND Dropout rates in binge eating disorder (BED) treatment are high (17-30%), and predictors of dropout are unknown. METHOD Participants were 376 patients following an intensive outpatient cognitive behavioural therapy programme for BED, 82 of whom (21.8%) dropped out of treatment. An exploratory logistic regression was performed using eating disorder variables, general psychopathology...

The transdiagnostic theory of eating disorders proposes that clinical perfectionism, core low self-esteem, interpersonal problems and mood intolerance can maintain eating disorder psychopathology in some individuals. The current study aimed to explore eating disorder symptom severity as a function of these maintaining mechanisms in a community sample. Participants completed questionnaires onlin...

We compared symptom patterns, severity of illness, and comorbidity in individuals with eating disorders with and without impulse control disorders (ICD), and documented the temporal pattern of illness onset. Lifetime ICD were present in 16.6% of 709 women with a history of eating disorders. The most common syndromes were compulsive buying disorder and kleptomania. ICD occurred more in individua...

This study examined the clinical significance of the loss of control over eating as a key component of eating disorders. It investigated the association of eating-related psychopathology and general psychopathology with objective bulimic episodes (OBEs; experiencing a loss of control while consuming large amounts of food) and subjective bulimic episodes (SBEs; experiencing a loss of control whi...

OBJECTIVE Adoption of effective treatments for recurrent binge-eating disorders depends on the balance of costs and benefits. Using data from a recent randomized controlled trial, we conducted an incremental cost-effectiveness analysis (CEA) of a cognitive-behavioral therapy guided self-help intervention (CBT-GSH) to treat recurrent binge eating compared to treatment as usual (TAU). METHOD Pa...

OBJECTIVE The dopaminergic system is associated with feelings of pleasure and reward and with positive hedonic processes related to food, sexual activity and certain substances. Because it is recognized that patients who have eating disorders with binge-eating behaviour have a high comorbidity of substance dependence, we examined the association between the variable number of tandem repeats (VN...

OBJECTIVE Eating disorders develop through a combination of genetic vulnerability and environmental stress, however the genetic basis of this risk is unknown. METHODS To understand the genetic basis of this risk, we performed whole exome sequencing on 93 unrelated individuals with eating disorders (38 restricted-eating and 55 binge-eating) to identify novel damaging variants. Candidate genes ...

objective: the aim of this study was to provide norms of eating disorder examination questionnaire (ede-q) and clinical impairment assessment (cia) for undergraduate women in iran. materials and methods: ‎undergraduate women (n = 516) completed the ede-q, cia, and the binge eating scale (bes). results : average score, standard deviation, and percentile rank of ede-q and its subscale as well ‎as...

Scientific interest in "food addiction" is growing, but the topic remains controversial. One critique of "food addiction" is its high degree of phenotypic overlap with binge eating disorder (BED). In order to examine associations between problematic eating behaviors, such as binge eating and "food addiction," we propose the need to move past examining similarities and differences in symptomolog...

OBJECTIVE To determine if interpersonal problems reported by individuals with binge eating disorder (BED) are distinct from psychiatric norms, and whether specific types of interpersonal problems are predictive of BED treatment outcome. METHOD Subjects were 88 females with BED who completed a treatment trial for binge eating and weight loss. Pretreatment data on the Inventory of Interpersonal...