Background: Alzheimer’s disease (AD) is a neurodegenerative disease characterized by decreased cognitive function in patients due to forming Aβ peptides and neurofibrillary tangles (NFT) in the brain. Therefore, the need to develop new treatments can reduce this risk. Acetylcholinesterase is one of the targets used in the design of new drugs for the treatment of AD. The researchers obtain new i...

Evidence is presented which indicates that almost all HCGs are dynamically associated with generally elongated loose groups of galaxies, and are compact cores of the latter. Most of those loose groups, the direction of elongation of which lies at angles close to 45◦ with the line of sight, were revealed by previous investigations. Hence, HCGs have, probably, longer life-times than it has been d...

We propose a method to probe the nonlocality of a pair of Majorana bound states by crossed Andreev reflection, which is the injection of an electron into one bound state followed by the emission of a hole by the other (equivalent to the splitting of a Cooper pair). We find that, at sufficiently low excitation energies, this nonlocal scattering process dominates over local Andreev reflection inv...

a thermodynamic study on the interaction between zinc ion (zn2+) and human growth hormone(hgh) was studied at two temperatures of 27c and 37c in aqueous solution using an isothermal titrationcalorimetry. it was found that there is a set of three identical and non-interacting binding sites for zn2+ ions. the intrinsic dissociation equilibrium constant and the molar enthalpy of binding are 1.54...

Density functional theory (DFT) calculations were performed on tripeptide arginyl-glycyl-aspartic acid (RGD) as an efficient drug carrier to deliver the commercially famous cyclophosphamide (CP) anticancer drug within ethanol solution. The most negative binding energy (-5.22 kcal/mol) was measured for the CP-RGD-7 created through the H-bond interaction between the P=O (phosphoryl) oxygen atom o...

Solar cells incorporating organic-inorganic perovskite, which may be fabricated using low-cost solution-based processing, have witnessed a dramatic rise in efficiencies yet their fundamental photophysical properties are not well understood. The exciton binding energy, central to the charge collection process, has been the subject of considerable controversy due to subtleties in extracting it fr...