Internal Carotid Artery Occlusion Diagnosed by Doppler Ultrasound • Using a transcutaneous Doppler ultrasonic blood velocity detector, retrograde ophthalmic artery blood flow was demonstrated in four patients, all of whom had angiographically confirmed occluded internal carotid arteries. In three, compression of the facial artery obliterated the ophthalmic artery signal. In a fourth patient com...

We report a case of pituitary apoplexy resulting in right internal carotid artery occlusion accompanied by hemiplegia and lethargy. A 43-yr-old man presented with a sudden onset of severe headache, visual disturbance and left hemiplegia. Investigations revealed a nodular mass, located in the sella and suprasellar portion and accompanied by compression of the optic chiasm. The mass compressed th...

We developed a novel trans-femoral artery approach to the rat middle cerebral artery occlusion model (TF-MCAO) without sacrificing the external carotid artery (ECA) with/without the pterygopalatine artery, which is important for chewing food. To make the TF-MCAO we first dissect the left common carotid artery (CCA), ECA, and internal carotid artery (ICA). Transient occlusion clips are applied t...

Beraprost sodium is a new stable, orally active Prostaglandin I2 analogue. The aim of this study was to determine the effect of beraprost on cognitive dysfunction and locomotor impairment induced by bilateral common carotid artery occlusion in mice. We investigated the ameliorating effect of beraprost through PGI2 IP receptor by studying neurologic deficit assessment and T-maze testing in young...

BACKGROUND AND PURPOSE Ischemic injury in neurons can be strongly reduced by a preceding sublethal ischemic episode, of which the mechanism is poorly understood. Although changes in the expression of apoptosis-related proteins (Bcl-2, Bcl-xl, and Bax) have been considered to be crucially important in ischemic injury, the roles these proteins play in ischemic preconditioning induced by sublethal...

We report a case of progeria and the utility of visualizing the cerebrovascular anatomy by using MR angiography. A 4-year-old child with Hutchinson-Guilford syndrome developed symptoms of ischemia and MR angiography showed bilateral occlusion of internal carotid and vertebral artery origins; the anterior spinal artery was prominent.

Content/Summary Low pulsatile or non-pulsatile cerebral perfusion was noted in patients with aortic arch dissection, acute proximal internal carotid or common carotid artery occlusion and means impending large cerebral infarction. A 45-year-old man had a sudden aphasia and left hemispheric symptoms with NIHSS of 16 on arrival. Complete occlusion of left middle artery with leptomeningeal collate...

We retrospectively studied 46 patients with symptomatic retinal artery occlusion and assessed the pattern and extent of carotid artery disease ipsilateral to the retinal artery occlusion. Ipsilateral internal carotid artery atherosclerotic lesions were virtually limited to the cervical arterial segment; 50% of such lesions were plaques or stenoses of less than or equal to 60%, whereas 15% of th...