Oxidative stress results in structural and functional abnormalities in the liver and is thought to be a crucial factor in liver diseases. The aim of this study was to investigate the cytoprotective and antioxidant effects of caffeic acid (CA) derivatives on tert-butyl hydroperoxide (t-BHP)-induced oxidative stress in HepG2 cells. Nine CA derivatives were synthesized, including N-phenylethyl caf...

PURPOSE Oxidative stress is thought to contribute to the pathogenesis of age-related macular degeneration (AMD), which involves retinal pigmented epithelial (RPE) cell death. However, signaling pathways involved in the oxidative-stress-induced RPE cell death are poorly understood. This study was conducted to investigate the involvement of the MAP kinase pathways during the induction of RPE cell...

BACKGROUND The current study focuses on the comparison of postoperative muscular strength around the hip joint of patients with femoral intertrochanteric fractures treated either by cephalo-medullary (CM) nailing or a new bipolar hip prosthesis (BHP), an especially attached device to secure displaced greater trochanteric fragment. METHODS Twenty patients treated with CM nailing were age- and ...

1) Graduate School of Energy Science and Technology, Kyoto University. Yoshida Honmachi, Sakyoku, Kyoto, 606-8501 Japan. 2) Formerly Graduate Student, Graduate School of Eng., Hokkaido University. Now at Nippon Steel Corporation, Ohita Works, Nishi-no-su, Ohita, 870-0992 Japan. 3) Graduate School of Eng., Faculty of Engineering, Hokkaido University, Kita-13Jou, Nishi-8Choume, Kita-ku, Sapporo, ...

1) Graduate School of Energy Science and Technology, Kyoto University, Yoshida Honmachi, Sakyoku, Kyoto, 606-8501 Japan. 2) Formerly Graduate Student, Graduate School of Eng., Hokkaido University. Now at Nippon Steel Corporation. Ohita Works, Nishi-no-su, Ohita, 870-0992 Japan. 3) Graduate School of Eng., Faculty of Engineering, Hokkaido University. Kita-13Jou, Nishi-8Choume, Kita-ku, Sapporo, ...