Two structurally similar bis-phenanthridinium–adenine conjugates (equipped with one or two adenines, respectively), exhibiting strong ds-DNA/RNA groove binding, revealed ratiometric fluorescent recognition of alternating AT-DNA with respect to other ds-DNA/RNA and ss-RNA. Further, CD spectra pattern of adenine–bis-phenanthridinium conjugate/polynucleotide complexes strongly depended on polynucl...

Adenine phosphoribosyltransferase activity was measured in extracts of soybean (Glycine max var. Acme) callus and of senescing barley leaves (Hordeum distichon c.v. Prior). The enzyme from soybean callus had Michaelis constants for adenine and 5-phosphoribosyl pyrophosphate of 1.5 and 7.5 mum respectively and was inhibited by AMP and stimulated by ATP. The presence of kinetin was found to consi...

This communication explores the effect of varying substituent bulk at the N9 position of the adenine moiety and its effect in dictating the structural aspects of silver-adenine frameworks. While adenine alone or 9-benzyl substituted ligand afforded mono and dinuclear dimeric entities, n-propyl substitution at the N9 position results in the formation of a metallaquartet. Longer n-alkyl chains (h...

Rates of purine salvage of adenine and hypoxanthine into the adenine nucleotide (AdN) pool of the different skeletal muscle phenotype sections of the rat were measured using an isolated perfused hindlimb preparation. Tissue adenine and hypoxanthine concentrations and specific activities were controlled over a broad range of purine concentrations, ranging from 3 to 100 times normal, by employing...

Three cytokinin-over-producing mutants of the moss, Physcomitrella patens, have been shown to convert [8-(14)C]adenine to N(6)-[(14)C](Delta(2)-isopentenyl)adenine, the presence of which was confirmed by thin layer chromatography, high performance liquid chromatography, and recrystallization to constant specific radioactivity. The labeled cytokinin was detected in the culture medium within 6 ho...

abstract one of the most important cut foliage plants is strelitzia (strelitzia spp.) which has several usages. this research program was focused on increasing the vase life of strelitzia cut foliage in the normal storage condition. the experiment was arranged as completely randomized design with three replications. treatments included combinations of four different levels of gibberellic acid (...

field trials with ficus benjamina l.were conducted at the experimental farm of faculty of agriculture, university azad jiroft in 2012 growth seasons. the aim of this work is to study the effect of foliar application with gibberellic acid (ga3) and benzyladenine (ba) at 0, 100 and 200 mg.l-1 on the vegetative growth and photosynthetic pigments of ficus benjamina plants. the obtained results show...

Because adenine is effective for managing cases of radiation-induced and drug-induced leukopenia, it may be effective in cases of antipsychotic-induced leukopenia and neutropenia. Here, we report our experience with patients with leukopenia and neutropenia caused by an antipsychotic overdose or discontinuation of lithium carbonate, in whom adenine administration ameliorated the white blood cell...

By monitoring the growth of several adenine auxotrophs of the yeast Saccharomyces cerevisiae on cytokinin-supplemented media, we have demonstrated that this organism can utilize some of these derivatives as a source of adenine. Growth of a mutant lacking adenylosuccinate synthetase suggests that the conversion of cytokinins to adenine does not involve a hypoxanthine intermediate and may be cata...