the reaction of bis[4-hydroxy-3-methoxyphenyl]-1,6-heptadiene-3,5-dione (curcumin) and two novel ligands of bis[4-tetrabenzylglucose-3-methoxyphenyl]-1,6-heptadiene-3,5-dione (bis(tetrabenzylglucose)curcumin) (btbgc) and bis[4-tetraacetylglucose-3-methoxyphenyl]-1,6-heptadiene-3,5-dione (bis(tetraacetylglucose)curcumin) (btagc) with vanadium in methanol, in a 2:1 molar ratio, which yield the co...

144 Metabolomics studies of chronic atrophic gastritis cold and heat syndrome M.L. Wang, C.L. Zheng, Y.W. Zhou, T.G. Liu, Y.B. Li, H. Xie, Y. Chang, W.C. Liu, G.G. Chen, X.L. Sun, Y.H. Zhao, Z.H. Li 1 Beijing Jiangong Hospital, Beijing 100054,China 2 Beijing Gulou Hospital of Traditional Chinese Medicine, Beijing 100009, China 3 Beijing University of Chinese Medicine, Beijing 100029,China 4 Bei...

6-Aminocoumarin on treatment with oxalyl chloride gives coumarinyl-6-isocynate (1a-c) which on treatment with glycine gives 1H-3-[2'-oxo-2'H-benzopyran-6'-yl]-5-imidazolidine-2, 4-dione (2a-c). (2a-c) when refluxed with o-chlorobenzaldehyde, m-hydroxybenzaldehyde, 3,4-dimethoxybenzaldehyde and 3-nitrobenzaldehyde separately gives 1H-5-(2"-chlorobenzylidene)-3-(2'-oxo-2'H-benzopyran-6'-yl) imida...

Knowledge of the ability of the female reproductive system to metabolize environmental chemicals is critical not only from the standpoint of toxicity but also from infertility risk assessment. Benzo(a)pyrene (BaP) is a toxicant that is released into the environment from automobile exhausts, cigarette smoke, burning of refuse, industrial emissions, and hazardous waste sites. In exposed animals, ...

The metabolism of some steroids has been investigated in liver microsomal preparations from male germ-free and conventional rats. Hydroxylation of 4-[4-14C]androstene3,17-dione in positions 60 and 16~~ is about 2 and 1.5 times more efficient in germ-free than in conventional rats. The same is true for 6/3and Zol-hydroxylation of 4-[4J4C]pregnene-3,20-dione (about 1.6 and 1.2 times larger, respe...

BACKGROUND Biotransformation is an effective technique for the synthesis of libraries of bioactive compounds. Current study on microbial transformation of dihydrotestosterone (DHT) (1) was carried out to produce various functionalized metabolites. RESULTS Microbial transformation of DHT (1) by using two fungal cultures resulted in potent butyrylcholinesterase (BChE) inhibitors. Biotransformat...

The two-phase issue in the O(n) non-linear σ-model: a Monte-Carlo study Our paper [1] has motivated a comment [2] by A. Patrascioiu and E. Seiler which we reply in this note. The remarks in [2] concern three statements that the authors select from our paper: i) " The results for O(8) support the asymptotic freedom scenario ". The authors in [2] argue that at small˜β ≡ β/8 the O(8) is expected t...