In the crystal structure of the title compound, NH(4) (+)·PF(6) (-)·C(12)H(24)O(6), the cation is situated in the 18-crown-6 ring, forming a supra-molecular rotator-stator-like structure held by N-H⋯O hydrogen bonds. The six O atoms of the crown ether lie approximately in a plane [mean deviation 0.2129 (3) Å]; the N atom is displaced by 0.864 (3)Å from the centroid of the 18-crown-6 ring. The s...

The reaction of dimethyl-amine hydro-chloride, 18-crown-6 and ferric chloride in ethanol yields the title compound, (C(2)H(8)N)[FeCl(4)]·C(12)H(24)O(6), which exhibits an unusual supramolecular structure. The protonated dimethyl-amine contains one NH(2) (+) group, resulting in a 1:1 supra-molecular rotator-stator structure (CH(3)-NH(2) (+)-CH(3))(18-crown-6), through N-H⋯O hydrogen-bonding inte...

Vilsmeier-Haack reaction of 2,3,3-trimethyl-3H-benzo[g]indole, then aqueous basic work-up, leads to benzo[g]indol-2-ylidene- malondialdehydes. These react with various arylhydrazines and quinolin-2-ylhydrazine to form 3,3-dimethyl-2-(1-aryl-1H-pyrazol-4-yl)- 3H-benzo[g]indoles in good yields.

The diastereoselective addition of an allylic indium intermediate to chiral o-bromophenyl sulfinyl imine 4 proceeded with good levels of diastereoselectivity. The resulting homoallylic amine derivatives were transformed into lactams 7 and 12, which upon copper-mediated intramolecular N-arylation led to the formation of benzo-fused 1-azabicyclo[j.k.0]alkanes 8 and 13. Benzo-fused 2-allyl-substit...

A novel, versatile route to phosphorus- and carbon-substituted η(5)-phosphacyclohexadienyl complexes was developed. Reaction of the anionic 2,4,6-triphenylphosphinine iron complex [K([18]crown-6)(thf)2][Cp*Fe(PC5Ph3H2)] (1) with selected main group element electrophiles afforded the new complexes [Cp*Fe(2-endo-H-PC5Ph3H2)] (endo-3), [Cp*Fe(2-exo-H-PC5Ph3H2)] (exo-3), [Cp*Fe(1-Me-PC5Ph3H2)] (4),...

In the crystal structure of the title organic salt, C(3)H(10)NO(+)·IO(4) (-)·C(12)H(24)O(6), the protonated 2-meth-oxy-ethanaminium (CH(3)OC(2)H(4)-NH(3) (+)) cation forms a 1:1 supra-molecular rotator-stator complex with the 18-crown-6 mol-ecule via N-H⋯O hydrogen bonds. The (CH(3)OC(2)H(4)-NH(3) (+)) group is attached from the convex side of the bowl-shaped crown, in contrast to similar ammon...

The abilities of various mono and dimethyl derivatives of benzo(a)pyrene (BP) to initiate skin tumors in mice were determined by using a two-stage system of tumorigenesis. 11-Methylbenzo(a)pyrene was found to be approximately 3 times more active as a tumor initiator than was the parent hydrocarbon; 1-methyl benzo(a)pyrene was about twice as active as was BP. Substitution of a methyl group in po...