Telomerase is a ribonucleoprotein that synthesizes telomeric DNA on chromosomal ends. Telomerase activation has been seen in many immortal cell lines and cancers. Telomerase activity was analyzed in prostate carcinoma; in coexistent prostatic intraepithelial neoplasia (PIN), benign prostatic hyperplasia (BPH), atrophy and normal tissue; and in benign prostate glands. Telomerase activity was det...

Background: Benign prostate hyperplasia (BPH) is a classical age-related disease of the prostate, present in 20% of men at the age of 40 years with progression to 70% by the age of 60 years. BPH is associated with various lower urinary tract symptoms, which affect their day-to-day life. Materials and methods: Our objective was to evaluate the association between HER-2/neu, c-myc, p53, and clini...

Objective: To value the correlation of Prostate Volume with Uroflowmetry and IPSS on patients BPHwithout urinary retention that would be conducted at Dr. Soetomo 2015-2017. Method: This research usedretrospective descriptive study using secondary data from medical records to determine relationshipbetween (PV) International Prostatic Symptom Score (IPSS)of Benign Hyperplasia (BPH) without retent...

Abstract Aim Benign prostatic hyperplasia (BPH) is a non-malignant prostate gland enlargement of unknown cause that affects more than 50% men over 60 and the most common bladder outlet obstruction voiding symptoms. BPH treated primarily with watchful waiting, phytotherapy, medical or surgical options. In this study, we sought to examine different management practices in African urological centr...

Abstract Introduction Benign prostatic hyperplasia is a common pathology in patients over 40 years of age, with an important role male sexual health due to its association dysfunction, elevated proportion inactivity. Objective The objective this study evaluate the factors associated activity age diagnosis benign Methods A retrospective cross-sectional 331 confirmed between January 2021 and Nove...

It is widely believed that benign prostatic hyperplasia (BPH) is associated with aging. Thus, the question arises whether or not a correlation exists between the well known prostatic androgen and estrogen accumulation and aging. To address this question, we measured 5 alpha-dihydrotestosterone (DHT), testosterone, estradiol, and estrone in epithelium and stroma of six normal (NPR) and 19 BPH an...

INTRODUCTION Benign prostatic hyperplasia is a common disease of ageing men worldwide. Though transrectal ultrasonography (TRUS) is the standard in most parts of the world in evaluation of benign prostatic hyperplasia (BPH), it is rarely done in some less developed countries because of non availability of appropriate probes and or specialists. Transabdominal ultrasonography (TAUS) remains the m...

Peptide growth factors play an important role in several intracellular processes, such as cellular growth and differentiation, angiogenesis and apoptosis, as well as in carcinogenesis, since they contribute significantly to the malignant transformation. The prostate gland is abundant in growth factors. The two most known prostatic diseases, prostate cancer (PCa) and benign prostatic hyperplasia...