The objectives of this work were to optimize hydro-distillation extraction Salvia officinalis L. essential oil (SoEO) and evaluate the in vitro scavenging capacity free radicals DPPH·, NO·, ABTS+, ability reduce Fe3+. optimization SoEO by was carried out using response-surface methodology Box–Behnken. cytotoxicity anti-proliferative capacities evaluated measuring cell viability then modeled. Tw...

The present study aims to enhance the bioavailability of Blueberry by formulating it as nanosuspension. mainly consists ofanthocyanins which have strong antihyperlipidemic activity but suffers from low causes hindrances in itstherapeutic treat hyperlipidemia. Hence improve its bioavailability, nanosuspension blueberry was prepared. BoxBehnken design applied predict effect independent variables ...

The walnut green hull is an agro-waste, a source of natural dye and volatile compounds with various biological activities, but the main challenge conventional extraction method quality quantity compound (dye) from waste. objective this research work to use microwave-assisted (MAE) as emerging technology. Further, MAE process was optimized using Box–Behnken Design (BBD) response surface methodol...

objective(s): a box-behnken design was used for evaluation of eudragit coated diclofenac pellets. the purpose of this work was to optimize diclofenac pellets to improve the physicochemical properties using experimental design. materials and methods: diclofenac was loaded onto the non-pareil beads using conventional coating pan. film coating of pellets was done at the same pan. the effect of pla...

Objective: The objective of the selected study was to develop and statistically optimize fluconazole (drug) loaded pharmacosomes (carrier) enhance transdermal permeation by incorporating into gel base treat fungal infections selecting Box-Behnken model. Methods: Fluconazole is an antifungal drug which belongs BCS class-II with high permeability choice for topical delivery. In study, levels leci...