Local inhibitory circuits are thought to shape neuronal information processing in the central nervous system, but it remains unclear how specific properties of inhibitory neuronal interactions translate into behavioral performance. In the olfactory bulb, inhibition of mitral/tufted cells via granule cells may contribute to odor discrimination behavior by refining neuronal representations of odo...

Background: Diabetes mellitus is a common metabolic disorder worldwide. It imposes excessive psychological stress on patients which negatively affect the course of the disease. The brain-behavioral systems have a role in dealing with stressful events such as chronic disorders. Objective: Comparison the brain-behavioral systems and psychological distress in diabetic patients and non-diabetics. ...

Behavioral approach and avoidance are fundamental to the experience of emotion and motivation, but the motivational system associated with anger is not well established. Some theories posit that approach motivational processes underlie anger, whereas others posit that avoidance motivational processes underlie anger. The current experiment sought to address whether traits related to behavioral a...

Behavioral inhibition reflects a disposition to react warily to novel situations, and has been associated with atopic diseases such as asthma. Retrospective work established the relationship between behavioral inhibition in rhesus monkeys (Macaca mulatta) and airway hyperresponsiveness, but not atopy, and the suggestion was made that behavioral inhibition might index components of asthma that a...

Many common psychiatric conditions, such as attention deficit/hyperactivity disorder (ADHD), obsessive-compulsive disorder (OCD), Parkinson's disease, addiction and pathological gambling are linked by a failure in the mechanisms that control, or inhibit, inappropriate behavior. Models of rat behavioral inhibition permit us to study in detail the anatomical and pharmacological bases of inhibitor...

a University of California, Berkeley, Department of Psychology, 3210 Tolman Hall #1650, Berkeley, CA 94720, United States b University of Miami, Department of Psychology, PO Box 248185, Coral Gables, FL 33124, United States c Yale University, Department of Psychology, United States d Hussman Institute for Human Genomics, University of Miami Miller School of Medicine, 1501 NW 10th Ave, Miami, FL...

Behavioral inhibition (i.e. avoidance of unfamiliar) has been linked to significant differences in stress physiology and health. Developing an animal model of this common temperament provides a means to experimentally study the development and physiology of this trait as it relates to stress-related health processes. To elaborate such an animal model, we studied individual rat responses to two ...

Behavioral inhibition refers to a temperament or style of reacting that some infants and young children exhibit when confronted with novel situations or unfamiliar adults or peers. Research on behavioral inhibition has examined the link between this set of behaviors to the neural systems involved in the experience and expression of fear. There are strong parallels between the physiology of beha...

Behavioral flexibility and goal-directed behavior heavily depend on fronto-striatal networks. Within these circuits, gamma-aminobutyric acid (GABA) glutamate play an important role in (motor) response inhibition, but it has remained largely unclear whether they are also relevant for cognitive inhibition. We hence investigated the functional of transmitters inhibition during flexibility. Healthy...