Our group and others have determined that immune effector cells from patients with advanced cancers exhibit reduced activation of IFN signaling pathways. We hypothesized that increases in immune regulatory cells termed myeloid-derived suppressor cells (MDSC) could interfere with the host immune response to tumors by inhibiting immune cell responsiveness to IFNs. The C26 murine adenocarcinoma mo...

in this paper, static performance characteristics for a finite lenght two-lobe journal bearing lubricated with micropolar fluid is studied. using finite element method, steady-state film pressure is obtained by solving modified reynolds equation, based on micropolar lubrication theory. with the help of film pressure in bearing, the static performance characteristics in terms of load carrying ca...

The paper deals with the experimental characterization of different 280 mm diameter tilting pad journal bearings for turbomachines using a dedicated test rig. articles were 5-pad Direct Lube Rocker Pivot bearing, Flooded and 4-pad Ball Socket bearing. three tested in their specific design range operating conditions. Their static dynamic behavior was investigated as function parameters. In parti...

air spindles are one of the main elements of precise machine tools. vibration of these spindles is one of the vital issues necessary for investigation. among parameters which influence air spindle vibrations are rotational speed, compression air method, input nozzle diameter, air gap pressure. in this study using ansys, the effects of air gap thickness on air spindle vibrations have been invest...

in this paper the problem on “magnetic fluid lubrication of porous-pivoted slider bearing with slip velocity by n ahmad et.al.[7]” has been recapitulated using jenkin’s model [4] with the additional effect of squeeze velocity of the above plate. it is found that while discussing the above problem, [7] has stated but ignored the term , where +, in their study (refer equation(2.2)). this paper re...

The src homology region 3 (SH3) domain-bearing protein Bem1p and the Rho-type GTPase Cdc42p are important for bud emergence in Saccharomyces cervisiae. Here, we present evidence that through its second SH3 domain, Bem1p binds to the structurally and functionally similar proteins Boi1p and Boi2p, each of which contain an SH3 and pleckstrin homology (PH) domain. Deletion of BOI1 and BO12 together...

Ball bearings are commonly used in inverter-driven electrical machines, where they can be subject to high-frequency common-mode currents that accelerate their degradation. This article investigates the impact of shaft speed, voltage amplitude, and frequency on bearing impedance, including during discharges, with aim provide an experimentally validated approach model behavior as a function opera...

BACKGROUND Posterior-stabilized total knee prostheses were introduced to address instability secondary to loss of posterior cruciate ligament function, and they have either fixed or mobile bearings. Mobile bearings were developed to improve the function and longevity of total knee prostheses. In this study, the International Consortium of Orthopaedic Registries used a distributed health data ne...

Abstract In order to study the transmission characteristics of vibration in shafting optoelectronic equipment, a horizontal test platform for equipment is designed. Firstly, according special structure and load conditions three-row ball-column combined turntable bearing used shafting, quasi-static model was established solve distribution further calculate stiffness. At same time, system establi...

A finite element program based on elastic –plastic model of Mohr-Coulomb criterion was used to evaluate the bearing capacity coefficients of soil under shallow strip flexible footing . The results were compared with others’ analytical results and it was found that the present study could offer quite consistent and rather precise values for the bearing capacity coefficients . The effect of d...