We used personal air samplers to measure indoor air exposure to polybrominated diphenyl ethers (PBDEs) for 20 residents of the Greater Boston Area (Massachusetts). Area air measures were simultaneously collected from two rooms in each participant's home. Total personal air concentrations (particulate + vapor) were 469 pg/m3 for non-209 BDEs and 174 pg/m3 for BDE 209, significantly higher than b...

The influence of the type smoking process (natural/liquid; hot/cold) and salt (NaCl or KCl) on levels polybrominated diphenyl ethers (PBDEs) polycyclic aromatic hydrocarbons (PAHs) in smoked salmon was evaluated. One parent compound - BDE 47 two methoxylated forms 2?-MeO-BDE-68 6-MeO-BDE-47 were detected all samples. Among 14 PAHs analysed, naphthalene most abundant followed by phenanthrene flu...

The present study shows the occurrence of 2,2',3,3',4,4',5,5',6,6'-decabromodiphenyl ether (BDE-209) in microbial biofilms of Pyrenean and Tatra high mountain lakes despite its low vapor pressure and high hydrophobicity. Aerosol air transport is therefore a feasible mechanism for BDE-209 accumulation in sites up to 2688 m above sea level. This compound and other PBDEs exhibit altitudinally-depe...

A chemical microsolvation model for solution phase bond dissociation enthalpy (BDE) evaluation by means of molecular dynamics is presented. In this simple model, the primary solvent effect on the BDE values was estimated by placing of fi ve water molecules nearby the studied functional groups evenly. Furthermore, the secondary solvent effect was refl ected using the conductor like screening mod...

Portal fibroblasts (PF) are fibrogenic liver cells distinct from hepatic stellate cells (HSC). Recent evidence suggests that PF may be important mediators of biliary fibrosis and cirrhosis. The cytokine monocyte chemoattractant protein-1 (MCP-1)/CCL2 is upregulated in biliary fibrosis by bile duct epithelia (BDE) and induces functional responses in HSC. Thus we hypothesized that release of MCP-...

Taihu Lake area is one of the densest metropolitan areas in the world including diverse industrial activity. In the present study, the snail (Bellamya aeruginosa) and sediment were collected from the Taihu Lake area to investigate the contamination status, congener pattern, spatial distribution, and bioaccumulation effect of polychlorinated biphenyls (PCBs) and polybrominated diphenyl ethers (P...

BACKGROUND Organohalogen compounds (OHCs) are known to have neurotoxic effects on the developing brain. OBJECTIVE We investigated the influence of prenatal exposure to OHCs, including brominated flame retardants, on motor, cognitive, and behavioral outcome in healthy children of school age. METHODS This study was part of the prospective Groningen infant COMPARE (Comparison of Exposure-Effec...

The support vector machine (SVM), as a novel type of learning machine, was used to develop a Quantitative Structure-Property Relationship (QSPR) model of the O-H bond dissociation energy (BDE) of 78 substituted phenols. The six descriptors calculated solely from the molecular structures of compounds selected by forward stepwise regression were used as inputs for the SVM model. The root-mean-squ...

37 PBDE congeners were analyzed at six different depths in two soil cores taken from a typical electronic waste polluted area in South China. The PBDEs were congregated in the surface layer (0-5 cm) of soil cores and were 29 times in MK and 18 times in NW higher than the second lower layers (5-10 cm). As a whole, the concentrations of PBDEs were decreased with the soil depth increased in two co...

High concentrations of polybrominated diphenyl ethers (PBDEs) and their structural analogues (such as methoxylated (MeO) and hydroxylated (OH) PBDEs) had been observed in environmental samples and human tissues. This study evaluated the occurrence, potential source and human exposure of these organobrominated compounds via market fish consumption in Hong Kong. The contamination of 22 PBDEs, 7 M...