Sorption of uranium (VI) from aqueous solution onto powdered corn cob has been carried out using batch and fixed-bed technique. The experimental results in batch technique were fitted well with pseudo second-order kinetics model. In the fixed bed technique, Thomas and Bohart-Adams models were evaluated by linear regression analysis for U(VI) uptake in different flow rates, bed heights and initi...

biopharmaceuticals continues to increase from an estimated $12 billion three years ago to $30 billion today. Of the 122 biopharmaceutical products approved in the United States and Europe, 50 are produced using mammalian cells, 39 by prokaryotic cells, 21 using a yeast system, and a further 12 products by undisclosed systems (1). As an increasing number of potential new drugs emerge from the pr...

Real-world knowledge discovery processes typically consist of complex data pre-processing, machine learning, evaluation, and visualization steps. Hence a data mining platform should allow complex nested operator chains or trees, provide transparent data handling, comfortable parameter handling and optimization, be flexible, extendible and easy-to-use. Depending on the task at hand, a user may w...

Introduction Single-Use Bioreactors are now commonly used for Process Development activities, as seeding bioreactors or to produce Drug Substances. The advantages of this equipment have been well demonstrated over the last years on batch/fed-batch processes. Continuous processes were widely applied in the past to increase the overall productivity of small bioreactors or for sensitive molecule p...

Introduction. The program SEQIN-ST helps entering and analysing nucleic acid sequences and protein sequences using personal computers of the ATARI ST series. It allows the manual entry and/or the direct entry from a sequencing gel using the graphic mouse. The user decides the entry mode and the layout of the sequence. In check mode the sequence can be entered a second time and is automatically ...

Detecting high-z GRBs is important for constraining the GRB formation rate, and tracing the history of re-ionization and metallicity of the universe. Based on the current sample of GRBs detected by Swift with known redshifts, we investigated the relationship between red-shift, and spectral and temporal characteristics, using the BAT event-by-event data. We found red-shift trends for the peak-fl...

Batch codes, introduced by Ishai, Kushilevitz, Ostrovsky and Sahai, represent the distributed storage of an n-element data set on m servers in such a way that any batch of k data items can be retrieved by reading at most one (or more generally, t) items from each server, while keeping the total storage over m servers equal to N . This paper considers a class of batch codes (for t = 1), called c...

A number of manifold learning algorithms have been recently proposed, including locally linear embedding (LLE). These algorithms not only merely reduce data dimensionality, but also attempt to discover a true low dimensional structure of the data. The common feature of the most of these algorithms is that they operate in a batch or offline mode. Hence, when new data arrive, one needs to rerun t...

Industrial fermentations conducted in a batch or semi-batch mode demonstrate significant batch-tobatch variability. Current batch process monitoring strategies involve manual interpretation of highly informative but low frequency offline measurements such as concentrations of products, biomass and substrates. Fermentors are also fitted with computer interfaced instrumentation, enabling high fre...

Although serum-free media have been widely used in mammalian cell culture for therapeutic protein production, the effects of serum-substitutes on product quality have not been extensively examined. This study observed an adverse effect of Primatone RL, an animal tissue hydrolysate commonly used as a serum-substitute to promote cell growth, on sialylation of interferon-gamma (IFN-gamma) derived ...