3 Universidade Federal do Rio de Janeiro, Escola de Enfermagem Anna Nery, Departamento de Enfermagem Fundamental, Rio de Janeiro, RJ, Brazil. ABSTRACT Objective: To analyze potential intravenous drug interactions, and their level of severity associated with the administration of these drugs based on the prescriptions of an intensive care unit. Method: Quantitative study, with a retrospective ex...

Patients with a polyherbal prescription are more likely to receive duplicate medications and thus suffer from adverse drug reactions. We conducted a population-based retrospective study to examine the items of Chinese herbal medicine (CHM) per prescription in the ambulatory care of traditional Chinese medicine (TCM) in Taiwan. We retrieved complete TCM ambulatory visit datasets for 2010 from th...

OBJECTIVE To characterize trends in outpatient antibiotic prescriptions in the United States DESIGN Retrospective ecological and temporal trend study evaluating outpatient antibiotic prescriptions from 2013 to 2015 SETTING National administrative claims data from a pharmacy benefits manager PARTICIPANTS. Prescription pharmacy beneficiaries from Express Scripts Holding Company MEASUREMENTS Annua...

OBJECTIVES To use primary care electronic health records (EHRs) to evaluate prescriptions and inappropriate prescribing in men and women at age 100. DESIGN Population-based cohort study. SETTING Primary care database in the United Kingdom, 1990 to 2013. PARTICIPANTS Individuals reaching the age of 100 between 1990 and 2013 (N = 11,084; n = 8,982 women, n = 2,102 men). MEASUREMENTS Main ...

To the Editor: In their article, “Hypertension Control in Community Health Centers Across China: Analysis of Antihypertensive Drug Treatment Patterns,” Wang et al.1 reported baseline information on antihypertensive prescriptions from 1,000 community health centers in China from March 2007 to the end of 2010. The number of treated hypertensive patients was 92,325 out of 249,830 patients with hyp...

OBJECTIVE To determine whether postdating delayed antibiotic prescriptions results in a further decrease (over usual delayed prescriptions) in antibiotic use. DESIGN Randomized controlled trial. SETTING A small rural town in Newfoundland and Labrador. PARTICIPANTS A total of 149 consecutive adult primary care patients who presented with acute upper respiratory tract infections. INTERVEN...

CONTEXT Interest in the role of fibrates intensified after the publication of the negative results from the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, which assessed therapy with fenofibrate plus statins. The evidence for clinical benefit in outcomes with the use of fibrates is heavily weighted on the use of the older fibrates such as gemfibrozil and clofibrate. OBJECTI...

BACKGROUND Many common drugs have not been licensed for use in children. METHODS This study evaluated the incidence of unlicensed and off-label prescriptions at the Department of Pediatrics during a period of six months. A total of 8,559 prescriptions for 4,282 children were processed. RESULTS Off-label and unlicensed prescriptions were found in 9.01% and 1.26% of all prescriptions, respect...

BACKGROUND The aim of this work is to estimate the French frequencies of dispensed psychotropic prescriptions in children and adolescents. Prevalence estimations of dispensed prescriptions are compared to the frequencies of use of psychotropic reported by 17 year-old adolescents. METHODS Prescription data is derived from national health insurance databases. Frequencies of dispensed prescripti...

OBJECTIVE Several tools have been introduced to evaluate the quality of prescribing. The aim of this study was to determine the quality of prescribing in hypertension and bronchial asthma in tertiary health care (THC) setting using the new Prescription Quality Index (PQI) tool and to assess the reliability of this tool. METHODS A prospective cross-sectional study was carried out for 2 months ...