نتایج جستجو برای: barrel

تعداد نتایج: 6652  

2013
Takehiro K. Sato Rodney K. Tweten Arthur E. Johnson

Perfringolysin O (PFO), a bacterial cholesterol-dependent cytolysin, binds a mammalian cell membrane, oligomerizes into a circular prepore complex (PPC) and forms a 250-Å transmembrane β-barrel pore in the cell membrane. Each PFO monomer has two sets of three short α-helices that unfold and ultimately refold into two transmembrane β-hairpin (TMH) components of the membrane-embedded β-barrel. In...

Journal: :The Journal of biological chemistry 2015
Philipp Oberhettinger Jack C Leo Dirk Linke Ingo B Autenrieth Monika S Schütz

Autotransporter proteins comprise a large family of virulence factors that consist of a β-barrel translocation unit and an extracellular effector or passenger domain. The β-barrel anchors the protein to the outer membrane of Gram-negative bacteria and facilitates the transport of the passenger domain onto the cell surface. By inserting an epitope tag into the N terminus of the passenger domain ...

Journal: :Behemoth 2013

2015
Daniel Quint

I consider identification of a symmetric, independent private values model with additively separable unobserved heterogeneity from observation of winning bids in English auctions. If the number of bidders N is observable, the model is identified given exogenous variation in N , and N need only take two values. If N is not observable, the model is identified if observations are available from au...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1986
E Welker H Van der Loos

In mice from 6 strains bred for different patterns of mystacial vibrissae, we studied the consequences of the presence of supernumerary whiskers for the sensory innervation of the vibrissal follicles and their cortical representation in the barrel field. The parameters were number of axons innervating individual vibrissal follicles, tangential area of individual barrels, and thickness of the la...

Journal: :The Journal of biological chemistry 2005
H Anne Eisenhauer Sofia Shames Peter D Pawelek James W Coulton

The hydroxamate siderophore receptor FhuA is a TonB-dependent outer membrane protein of Escherichia coli composed of a C-terminal 22-stranded beta-barrel occluded by an N-terminal globular cork domain. During siderophore transport into the periplasm, the FhuA cork domain has been proposed to undergo conformational changes that allow transport through the barrel lumen; alternatively, the cork ma...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1995
D A Steindler D Settles H P Erickson E D Laywell A Yoshiki A Faissner M Kusakabe

In light of a previous report suggesting that the brains of tenascin-deficient animals are grossly normal, we have studied the somatosensory cortical barrel field and injured cerebral cortex in postnatal homozygous tenascin knockout, heterozygote, and normal wild-type mice. Nissl staining, cytochrome oxidase, and Dil axonal tracing of thalamocortical axonal projections to the somatosensory cort...

Journal: :The Journal of Cell Biology 2005
Doron Rapaport

A multisubunit translocase of the outer mitochondrial membrane (TOM complex) mediates both the import of mitochondrial precursor proteins into the internal compartments of the organelle and the insertion of proteins residing in the mitochondrial outer membrane. The proposed beta-barrel structure of Tom40, the pore-forming component of the translocase, raises the question of how the apparent uni...

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