Acute Epstein-Barr virus (EBV) infection is associated with central and peripheral neurological complications such as meningitis, encephalitis, myelitis and radiculopathy in 0.5-7.5% of patients. The peripheral nervous system manifestations of acute EBV infection include mononeuropathy, mononeuritis multiplex, autonomic neuropathy, and polyradiculopathy. Brachial plexopathy in children and immu...

The Epstein-Barr virus (EBV) is a gamma-herpes virus which establishes latent, life-long infection in more than 95% of the human adult population. Despite its growth transforming capacity, most carriers control EBV associated malignacies efficiently and remain free of EBV+ tumors. Though EBV is controlled by a potent immune response, this virus uses latency to persist in vivo. This review summa...

A 9-year-old white boy developed a fatal primary Epstein-Barr virus (EBV) infection while receiving chemotherapy for acute lymphoblastic leukemia in remission. Histopathological findings at the height of the proliferative phase of the illness were compatible with a virally induced hemophagocytic syndrome. The infection spontaneously converted to complete aplasia of the bone marrow and lymph nod...

DNA methylation at CpG motifs provides an epigenetic route to regulate gene expression. In general, inverse correlation between hypermethylation and expression is observed. Epstein Barr-virus (EBV) infects people the EBV genome resides in nucleus where either its replication cycle initiates or it enters a long-term latency state viral becomes hypermethylated motifs. Viral shows largely with hyp...

Epstein-Barr virus (EBV), a herpes virus, is now accepted as a bona fide human tumor virus and has been found to be a risk factor for the development of multiple sclerosis (MS). Epidemiological studies and molecular virology have been combined to establish EBV’s causal roles in several lymphomas and carcinomas. The success of these combined approaches illustrates what insights will be needed to...

Epstein-Barr virus (EBV) is a tumor virus that establishes lifelong infection in most of humanity, despite eliciting strong and stable virus-specific immune responses. EBV encodes at least 44 miRNAs, most of them with unknown function. Here, we show that multiple EBV miRNAs modulate immune recognition of recently infected primary B cells, EBV's natural target cells. EBV miRNAs collectively and ...

Colorectal adenocarcinoma is the neoplastic proliferation of glandular tissue in distal gastrointestinal system and can be managed using surgical resection, novel chemotherapeutic regimens, radiation therapy. Epstein-Barr virus (EBV) a common double-stranded DNA that has potential to transform B-cells into lymphoproliferative disorders given presence particular conditions such as immunocompromi...

Systemic EBV+ T cell lymphoma of childhood manifests as a rapidly progressive, life-threatening disorder with fulminant clinical course. Of obscure aetiology, systemic may arise in concurrence primary Epstein Barr viral infection wherein infiltrating lymphocytes demonstrate monoclonal rearrangements within receptor (TCR) genes. delineates virus infected cytotoxic CD8+ or activated CD4+ cells an...

Epstein Barr virus (EBV) and Kaposi sarcoma associated herpesvirus (KSHV) are two oncogenic human γ-herpesviruses that each with 1-2% of tumors. They encode bona fide oncogenes they express during latent infection to amplify their host cells themselves within these. In contrast, lytic particle producing has been considered destroy might be even induced therapeutically eliminate EBV KSHV However...