A 58-year-old man presented with complaints of epigastric pain for 2 years, recurrent vomiting containing stale food, and weight loss of 10 kg in the previous 3 months. He had been started on tablet mesalamine at a secondary care center for suspicion of Crohn’s disease, but there was no improvement in his symptoms. Barium meal study suggested multiple oval-shaped filling defects in his stomach ...

We have studied 80 patients with pernicious anaemia. Upper gastrointestinal endoscopy (with biopsy and cytology) showed no lesion other than atrophic gastritis in 34 patients. Thirty three patients, however, had varying degrees of gastric mucosal dysplasia, which was detected more frequently by histology than by cytology. The endoscopic appearance of the mucosa was abnormal in four of the six p...

A prospective study of the endoscopic, radiological, and surgical features of chronic duodenal ulceration has been performed. Double contrast barium meal and upper gastrointestinal endoscopy were both performed within five days of elective surgery for chronic duodenal ulceration on 50 patients. The surgical diagnosis correlated with endoscopy in 88% and radiology in 82%, but if both techniques ...

A severely affected case of Hartnup disease is reported, where the patient responded rapidly to nicotinamide. This supports the view that all the clinical features, except reduced stature from general nutritional defect, are secondary to tryptophan and nicotinamide deficiency rather than to an unknown toxic factor. Severe malabsorption of both tryptophan and phenylalanine was demonstrated. The ...

Nail-patella syndrome is a rare autosomal dominant disorder with characteristic skeletal and renal abnormalities, most commonly dysplastic nails, hypoplastic/absent patellae, and asymptomatic urinary abnormalities Box 3 Final diagnosis Nail-patella syndrome or hereditary onycho-osteodysplasia. A 52-year-old man presented with a history of colicky epigastric pain, intermittent upper abdominal di...

A 22-year-old male patient presented with the complaints of upper abdominal colicky pain, intermittent bilious vomiting, and abdominal distension of 3-month duration. There was no history of peritonitis, abdominal surgery, or long-term medication. Clinical examination was unremarkable. Routine laboratory investigations revealed hemoglobin of 11 gm/dL, erythrocyte sedimentation rate (ESR) of 80 ...

BACKGROUND Intestinal dysmotility and stasis after intestinal transplantation are considered to promote bacterial overgrowth and translocation. Two prokinetic agents, KW5139 (13-leu-motilin) and the somatostatin analogue octreotide acetate, were studied to determine whether they can ameliorate intestinal dysmotility during the early postoperative period. MATERIALS AND METHODS Motility was rec...

Smoking in Hospitals K. P. Ball, F.R.C.P ....................... 453 Active Management of Labour J. S. Crawford, F.F.A.R.C.S ................. 453 Intensive Care in a District General Hospital G. S. Crockett, F.R.C.P ................... 454 Radiological Evaluation of Pulmonary Metastases A. W. O'Malley, M.B., D.M.R.D., and M. R. P. Shaw, M.B., D.M.R.D ..................... 454 Tests of Acupunct...

A survey of all gastroenterologists in the Trent region showed that the number of upper GI endoscopies had doubled to 7.6 per 1000 of the population from 1981 to 1986, equalling the number of barium meals. Colonoscopies had increased from 0 39 to 0.94 per 1000 of the population. There had been a large increase in the proportion of endoscopies done by surgeons. There were 0.37 ERCP examinations ...

loss of 10 kg over the last year. She reported helping the passage of the food bolus through the subcutaneous presternal digestive conduit with her ngers. A thick-paste barium transit study revealed multiple diverticular pouches in the neoesophagus, with retained contrast material inside of them. No other reason for the weight loss was identi ed. As the dysphagia in this case seemed not to be w...