because of less systemic side effects of topical medications in pain relief of the painful form of diabetic peripheral neuropathy, this study aimed to compare the effect of amitriptyline and capsaicin cream in relieving pain in this condition. in this randomized, double-blind and non -inferiority trial, 102 patients received amitriptyline 2% and capsaicin 0.75% creams  3 times a day for 12 week...

nitric oxide (no) is an important molecule synthesized during wound repair. studies have reported the use of no donors on cutaneous wound repair, but their effects in different phases of healing are not elucidated. the aim of this work was to investigate the effects of topical sildenafil on wounds in rats. sildenafil (25 mg) was topically applied once daily on wound in treatment groups. on days...

Although TGs have been shown to be efficient in treatment of various skin diseases, their use can result in both local and systemic side effects. Some of the local side effects are skin atrophy, rosacea, and corticoid acne, while the major systemic side effects are hypothalamic-pituitary-adrenal-axis suppression along with diabetes mellitus and hypertension [1,7-9]. Mometasone furoate (MF) is a...

BACKGROUND Pain is a common adverse effect of dermatological laser procedures. Currently, no standard topical anaesthetic cream exists for deeper dermal laser procedures. OBJECTIVES To compare the efficacy of lidocaine/tetracaine cream and lidocaine/prilocaine cream in reducing self-reported pain during deeper dermal laser treatment of acne keloidalis nuchae (AKN) and tattoos. METHODS We co...

Date palm fruit is consumed as fresh fruit or processed to produce date paste and date syrup. Date syrup (DS) a natural sweetener contains mainly glucose and fructose and used with different food products. The effect of substituting sucrose with different level of DS (0, 25, 50 and 100%) on the physiochemical and sensory properties of ice cream were investigated. The overrun increased with incr...

BACKGROUND Topical analgesia is becoming essential as the number of invasive screening procedures involving children rises steadily. Little is known about the frequency of these procedures, or about interventions to ease the pain. METHODS We investigated the use of EMLA cream in 184 school-aged children in KwaZulu-Natal Province, South Africa. Another group of 20 children did not receive any ...

Neurodegeneration of the central and peripheral nervous system associated with hypocupremia and hyperzincinemia has been widely recognized but the origin of high zinc remained unknown. Denture cream has been recently suggested as one possible source of zinc, but the frequency with which denture fixative alone accounts for this syndrome is unknown. We analyzed the origin of excessive zinc in ele...

The market sales of premium ice cream have paralleled the growth in consumer desire for rich flavor and taste. Storage temperature is a major consideration in preserving the quality attributes of premium ice cream products for both the manufacturer and retailers during prolonged storage. We investigated the effect of storage temperature (-18℃, -30℃, -50℃, and -70℃) and storage times, up to 52 w...

PURPOSE Radiation dermatitis is a common side effect of radiation therapy (RT). In severe cases, RT must be interrupted until the skin heals, which can compromise treatment. The purpose of the study was to compare an anionic polar phospholipid (APP)-based cream and an aloe vera-based gel to determine their effectiveness in preventing and treating radiation dermatitis. PATIENTS AND METHODS For...