BACKGROUND Leishmaniasis has been identified as a major public health problem in tropical and sub-tropical countries. The present study was aimed to investigate antileishmanial effects of various extracts of Berberis vulgaris also its active compoenent, berberine against Leishmania tropica and L. infantum species on in vitro experiments. METHODS In this study in vitro antileishmanial activity...

Breast cancer is second most common in women and accounts for 23% of all occurring cancers in women. At present, more than 60% of the chemotherapeutic drugs are developed from plants and their derivatives, which can be used for development of anticancer drugs. An Indian barberry, Berberis aristata has been traditionally used for the treatment of inflammation, skin diseases, ulcers and cancers. ...

Meadow, a 15-year-old female patient, returns to Dr. Medical Derm (MD) with her father for severe nodulocystic acne that has been treated over many months. She has been compliant with the use of topical treatments (retinoid and benzoyl peroxide) and an oral antibiotic medication but the acne has not improved. The patient and her father are worried about scarring around her jawline. During the l...

OBJECTIVE Barberry root extract contains various alkaloids that are considered as antioxidants. Beneficial effect of aqueous extract of Berberis integerrima root (AEBIR) was evaluated for renal function in diabetic rats induced by STZ. MATERIAL AND METHODS Diabetes was induced by i.p. injection of streptozotocin (65 mg/kg bw) to rats, after 15 h of fasting. Diabetic rats were randomly grouped...

BACKGROUND Virus-induced dendritic cells (DCs) functional deficiency leads to sub-optimal initiation of adaptive immune responses and consequently chronic infection establishment. The present study reports an advanced hepatitis C virus (HCV) therapeutic vaccine model based on In vivo enrichment of DCs with barberry ethanolic crude extract (BCE) then pulsing them with HCV core protein. METHODS...

Acne is a cutaneous pleomorphic disorder of the pilosebaceous unit involving abnormalities in sebum production and is characterized by both inflammatory (papules, pustules and nodules) and no inflammatory (comedones, open and closed) lesions. Propionibacterium acnes and Staphylococcus epidermidis are common pus-forming microbes responsible for the development of various forms of, acne vulgaris....